Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 8/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623901 | 0.85 | CRHR1 (0.34) | CRHR1ADORA1HTR2BADORA3ADORA2A | |
| SCHEMBL5049413 | 0.72 | CRHR1 (0.35) | CRHR1ADORA1ADORA3 | |
| SCHEMBL5626968 | 0.71 | BCDIN3D (0.35) | CRHR1ADORA1ADORA3ADORA2A | |
| SCHEMBL5132599 | 0.69 | CRHR1 (0.36) | CRHR1ADORA1HTR2BADORA3ADORA2A | |
| SCHEMBL5133331 | 0.67 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL5043548 | 0.60 | IRAK4 (0.40) | — | |
| SCHEMBL16722921 | 0.60 | NOS3 (0.34) | — | |
| SCHEMBL10630036 | 0.57 | ALDH1A1 (0.37) | — | |
| SCHEMBL27311076 | 0.57 | TYR (0.44) | — | |
| SCHEMBL12354215 | 0.57 | MAPK14 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981342-B1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDYS LAB LTD DR (IN) | 2016-11-30 | — | — | EP | disclosed |
| EP-1981342-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007075194-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2007-07-05 | — | — | WO | disclosed |