Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623905 | 0.83 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL5042709 | 0.74 | PARP14 (0.38) | CRHR1 | |
| SCHEMBL2395175 | 0.73 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL5049417 | 0.71 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL5626979 | 0.70 | PDE10A (0.34) | CRHR1 | |
| SCHEMBL14698256 | 0.68 | RXRA (0.35) | CRHR1 | |
| SCHEMBL5132600 | 0.68 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL14833512 | 0.68 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL5046447 | 0.67 | GRM2 (0.37) | CRHR1 | |
| SCHEMBL5133328 | 0.67 | CRHR1 (0.32) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981342-B1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDYS LAB LTD DR (IN) | 2016-11-30 | — | — | EP | disclosed |
| EP-1981342-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007075194-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2007-07-05 | — | — | WO | disclosed |