Glycerin

Glycerin

SCHEMBL5133808

CC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OCC(O)CO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.56
LMNA P02545 3/20 0.52
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
USP2 O75604 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.32
TOP1 P11387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL5729048 1.00 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL27398 0.93 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL17931825 0.93 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL16491025 0.93 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL16968414 0.93 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL671091 0.93 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL9961490 0.93 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL342905 0.93 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL13998184 0.93 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL30497482 0.93 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200405797-A1 TRANSMUCOSAL DELIVERY DEVICE AND METHOD OF MANUFACTURING SAME NANOSTRIPS, INC. (US) 2020-12-31 US claimed
US-20050238605-A1 Low-viscosity O/W emulsion BEIERSDORF AG 2005-10-27 US claimed
EP-0932386-B1 COSMETIC AND SKIN CARE STICKS WITH HIGH WATER CONTENTS BEIERSDORF AG (DE) 2004-09-08 EP claimed
CN-118354749-A Kit and method for treating skin 莱雅公司 2024-07-16 CN disclosed
CN-118201589-A Cosmetic composition comprising a high amount of ceramide-NP 莱雅公司 2024-06-14 CN disclosed
CN-114599345-A Hair styling preparation 拜尔斯道夫股份有限公司 2022-06-07 CN disclosed
US-20200405797-A1 TRANSMUCOSAL DELIVERY DEVICE AND METHOD OF MANUFACTURING SAME NANOSTRIPS, INC. (US) 2020-12-31 US disclosed
US-7381423-B2 Use of nanodispersions in cosmetic end formulations CIBA SPECIALTY CHEMICALS CORP. (US) 2008-06-03 US disclosed
US-7008638-B2 Use of nanodispersions in cosmetic end formulations CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-03-07 US disclosed
US-20050238605-A1 Low-viscosity O/W emulsion BEIERSDORF AG 2005-10-27 US disclosed
US-20050238605-A1 Low-viscosity O/W emulsion BEIERSDORF AG 2005-10-27 US disclosed
US-20050191330-A1 Easily prepared carrier systems for wide range of active agents and oil soluble dyes; homogeneous ethanol and water clear liquid containing phospholipid, endcapped polyoxyethylene coemulsifier and lipophilic triglyceride; wide pH range CIBA SPECIALTY CHEMICALS CORP. 2005-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050191330-A1 Easily prepared carrier systems for wide range of active agents and oil soluble dyes; homogeneous ethanol and water clear liquid containing phospholipid, endcapped polyoxyethylene coemulsifier and lipophilic triglyceride; wide pH range LIPA, CETP, LIPC PDE4A 2968/4885LMNA 687/4885L3MBTL1 3220/4885
US-20050238605-A1 Low-viscosity O/W emulsion POLH, DGAT2, POLQ PDE4A 2596/4885LMNA 3912/4885L3MBTL1 2823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.