Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134837 | 0.88 | STAT3 (0.48) | ABCG2TERTSTAT3STAT1TOP1 | |
| SCHEMBL5013009 | 0.86 | STAT3 (0.49) | ABCG2TERTSTAT3STAT1TOP1 | |
| SCHEMBL5135317 | 0.81 | ABCG2 (0.41) | KDM1AABCG2TERTSTAT3STAT1 | |
| SCHEMBL949511 | 0.79 | TERT (0.57) | ABCG2MAPTRAB9ASMN1; SMN2TERT | |
| SCHEMBL29414382 | 0.79 | TERT (0.57) | ABCG2MAPTRAB9ASMN1; SMN2TERT | |
| SCHEMBL5134205 | 0.78 | STAT3 (0.43) | ABCG2TERTSTAT3STAT1TOP1 | |
| SCHEMBL2338257 | 0.78 | TERT (0.55) | ABCG2MAPTRAB9ASMN1; SMN2TERT | |
| SCHEMBL8430292 | 0.78 | TERT (0.55) | ABCG2MAPTRAB9ASMN1; SMN2TERT | |
| SCHEMBL20856304 | 0.78 | TERT (0.59) | ABCG2MAPTRAB9ASMN1; SMN2TERT | |
| SCHEMBL22265228 | 0.78 | TERT (0.55) | ABCG2MAPTRAB9ASMN1; SMN2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417142-B2 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2006-02-09 | — | — | US | disclosed |
| US-6951935-B2 | Heteroatom-substituted porphyrins and methods for synthesis of same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2005-10-04 | — | — | US | disclosed |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-06-09 | — | — | US | disclosed |
| US-20030236400-A1 | Heteroatom-substituted porphyrins and methods for synthesis of same | UNIVERSITY OF TENNESSEE RESEARCH CORPORATION | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | PPOX, HCCS, ICOSLG | KMT2A 1748/4885KDM1A 1679/4885POLB 1754/4885 |
| US-20030236400-A1 | Heteroatom-substituted porphyrins and methods for synthesis of same | PPOX, HMBS, UROD | KMT2A 1103/4885KDM1A 3116/4885POLB 1367/4885 |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | PPOX, PPIF, HMBS | KMT2A 2709/4885KDM1A 3012/4885POLB 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.