Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.35 |
| ▸ | LPL | P06858 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076866 | 0.72 | ALDH1A1 (0.41) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL31023154 | 0.72 | ALDH1A1 (0.41) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2723964 | 0.72 | LPL (0.40) | F11LIPGLPLCA1CA2 | |
| SCHEMBL826713 | 0.72 | LPL (0.40) | F11LIPGLPLCA1CA2 | |
| SCHEMBL22886631 | 0.71 | LPL (0.39) | F11LIPGLPLCA1CA2 | |
| SCHEMBL14746261 | 0.70 | LPL (0.36) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL16238349 | 0.70 | F11 (0.36) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2825036 | 0.70 | F11 (0.36) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2029210 | 0.69 | JAK2 (0.39) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1347543 | 0.69 | MAPK14 (0.39) | F11F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138843-A1 | IMIDAZOPYRIDINES AND TRIAZOLOPYRIMIDINES USEFUL FOR THE TREATMENT OF JOINT DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS N.V. (BE) | 2008-11-20 | — | — | WO | disclosed |