Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826713 | 0.73 | LPL (0.40) | LPLLIPGP2RX7CA1CA2 | |
| SCHEMBL2723964 | 0.73 | LPL (0.40) | LPLLIPGP2RX7CA1CA2 | |
| SCHEMBL22886631 | 0.72 | LPL (0.39) | LPLLIPGP2RX7CA1CA2 | |
| SCHEMBL5134635 | 0.70 | F11 (0.38) | LPLLIPGP2RX7CA1CA2 | |
| SCHEMBL22802070 | 0.69 | LPL (0.33) | LPLLIPGP2RX7CA1CA2 | |
| SCHEMBL861866 | 0.69 | LMNA (0.43) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL2298163 | 0.67 | LPL (0.39) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL28476218 | 0.67 | ALDH1A1 (0.37) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL3529326 | 0.67 | LPL (0.37) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL1467753 | 0.67 | CYP2A6 (0.36) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033093-A1 | HETEROCYCLIC COMPOUNDS AS JANUS KINASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013033093-A1 | HETEROCYCLIC COMPOUNDS AS JANUS KINASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |