Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032290 | 0.86 | RARB (0.39) | GAANPC1RARB | |
| SCHEMBL595610 | 0.83 | GAA (0.43) | ADRB2ADRB1ADRB3GAAALDH1A1 | |
| SCHEMBL1747913 | 0.82 | ALDH1A1 (0.45) | GAAALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL1761310 | 0.77 | GAA (0.56) | ADRB2ADRB1ADRB3GAAALDH1A1 | |
| SCHEMBL1748134 | 0.73 | HDAC1 (0.41) | GAALMNAHSD17B10KDM4EHDAC1 | |
| SCHEMBL1747936 | 0.73 | ALDH1A1 (0.51) | GAAHTTALDH1A1LMNAMAPT | |
| SCHEMBL1748085 | 0.73 | GAA (0.36) | GAAALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL4232023 | 0.72 | LMNA (0.53) | ADRB2ADRB1ADRB3GAAALDH1A1 | |
| SCHEMBL15059305 | 0.69 | EPHX2 (0.44) | ADRB2ADRB1ADRB3GAAALDH1A1 | |
| SCHEMBL6154566 | 0.68 | ADRB2 (0.46) | ADRB2ADRB1ADRB3GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874317-A2 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | Bayer Pharmaceuticals Corporation (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006113919-A2 | ARYL ALKYL ACID DERIVATIVES FOR AND USE THEREOF | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |