Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154661 | 0.82 | PBRM1 (0.50) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL3260498 | 0.81 | PBRM1 (0.49) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL380738 | 0.80 | SRC (0.53) | ALDH1A1KDM4ENPC1LMNAPOLB | |
| SCHEMBL10952369 | 0.78 | ALDH1A1 (0.53) | ALDH1A1NPC1LMNAPOLBPTGS1 | |
| SCHEMBL1067890 | 0.78 | PTPRB (0.41) | ADRB2ADRB1ADRB3ALDH1A1LOXL2 | |
| SCHEMBL6154138 | 0.78 | ADRB2 (0.45) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL16871506 | 0.78 | ALDH1A1 (0.49) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL6153752 | 0.77 | KMT2A (0.54) | ADRB2ADRB1ADRB3ALDH1A1NPC1 | |
| SCHEMBL595610 | 0.77 | GAA (0.43) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL28359889 | 0.76 | PBRM1 (0.59) | ADRB2ADRB1ADRB3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499603-A1 | ANTIVIRAL LACTONE-UREAS | Bayer Aktiengesellschaft (DE) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003089421-A1 | ANTIVIRAL LACTONE-UREAS | BAYER HEALTHCARE AG (DE) | 2003-10-30 | — | — | WO | disclosed |