Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860267 | 0.84 | TERT (0.51) | TP53NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8505932 | 0.78 | SCN2A (0.63) | SMN1; SMN2MAPTALDH1A1HPGDGAA | |
| SCHEMBL5580375 | 0.78 | MGLL (0.60) | TP53RAB9ASMN1; SMN2MAPTMGLL | |
| SCHEMBL19414975 | 0.77 | HPGD (0.61) | TP53NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8194022 | 0.76 | HSP90AA1 (0.59) | MAPTALDH1A1HPGDMGLLHTT | |
| SCHEMBL22871620 | 0.75 | SMN1; SMN2 (0.97) | TP53NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL12505801 | 0.75 | MGLL (0.56) | NPC1MAPTALDH1A1HPGDGAA | |
| SCHEMBL6075470 | 0.75 | SMN1; SMN2 (0.74) | TP53NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5542468 | 0.74 | TP53 (0.75) | TP53NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8361539 | 0.74 | TP53 (0.75) | TP53NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3236999-A1 | GAS-FILLED MICROVESICLES FOR USE AS VACCINE | Bracco Suisse SA (CH) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102515-A1 | GAS-FILLED MICROVESICLES FOR USE AS VACCINE | BRACCO SUISSE SA (CH) | 2016-06-30 | — | — | WO | disclosed |
| EP-1877038-A2 | CELL-SURFACE DECORATION WITH ACTIVE AGENTS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006119121-A2 | CELL-SURFACE DECORATION WITH ACTIVE AGENTS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2006-11-09 | — | — | WO | disclosed |