Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.61 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18539446 | 0.85 | SMN1; SMN2 (0.51) | HPGDALDH1A1HTTHSP90AA1CACNA1B | |
| SCHEMBL7565510 | 0.82 | RAB9A (0.71) | HPGDALDH1A1HTTNPSR1NPC1 | |
| SCHEMBL4996605 | 0.81 | SCN2A (0.65) | HPGDALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL8194022 | 0.79 | HSP90AA1 (0.59) | HPGDALDH1A1HTTHSP90AA1CACNA1B | |
| SCHEMBL13931460 | 0.77 | HSP90AA1 (0.40) | HPGDALDH1A1HTTHSP90AA1CACNA1B | |
| SCHEMBL8505932 | 0.77 | SCN2A (0.63) | HPGDALDH1A1HTTHSP90AA1NPSR1 | |
| SCHEMBL7083417 | 0.77 | RAB9A (0.57) | HPGDALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL5134832 | 0.77 | TP53 (0.60) | HPGDALDH1A1HTTHSP90AA1CACNA1B | |
| SCHEMBL5580375 | 0.77 | MGLL (0.60) | HSP90AA1NPSR1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL9146676 | 0.77 | LMNA (0.68) | HPGDALDH1A1HTTNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2442839-B1 | BLOCK COPOLYMER BLENDS | UNIV QUEENSLAND (AU) | 2017-10-04 | — | — | EP | disclosed |