Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 13/20 | 0.60 |
| ▸ | FAAH | O00519 | 5/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194022 | 0.86 | HSP90AA1 (0.59) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL8505932 | 0.85 | SCN2A (0.63) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL12505801 | 0.85 | MGLL (0.56) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL8404261 | 0.83 | DDAH1 (0.59) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL12268629 | 0.83 | DDAH1 (0.59) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL9987985 | 0.80 | TGM2 (0.54) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| Water SCHEMBL28505362 | 0.79 | L3MBTL1 (0.61) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL12268614 | 0.79 | PTPN1 (0.56) | MGLLFAAHHSP90AA1PKMNPSR1 | |
| SCHEMBL12321793 | 0.79 | HSP90AA1 (0.84) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL12412306 | 0.78 | MEN1 (0.42) | MGLLFAAHHSP90AA1PKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072199-A1 | Covalent methods for immobilization of thiolated biomolecules on siliceous and metallic surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-03-29 | — | — | US | disclosed |
| US-20070072199-A1 | Covalent methods for immobilization of thiolated biomolecules on siliceous and metallic surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-03-29 | — | — | US | disclosed |
| WO-2004113872-A2 | COVALENT METHODS FOR IMMOBILIZATION OF THIOLATED BIOMOLECULES ON SILICEOUS AND METALLIC SURFACES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2004-12-29 | — | — | WO | disclosed |