Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 5/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5573467 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1ATAAR1SLC6A2CPA1 | |
| SCHEMBL10831201 | 0.76 | SLC6A2 (0.55) | SMN1; SMN2HIF1ATAAR1SLC6A2FDPS | |
| SCHEMBL9583022 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1ATAAR1SLC6A2CPA1 | |
| SCHEMBL1828129 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2HIF1ATAAR1SLC6A2CPA1 | |
| SCHEMBL5151339 | 0.74 | SLC6A2 (0.41) | SMN1; SMN2HIF1ATAAR1SLC6A2CPA1 | |
| SCHEMBL14935688 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2HIF1ATAAR1SLC6A2CPA1 | |
| Hydrochloric Acid SCHEMBL9582760 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2HIF1ATAAR1SLC6A2FDPS | |
| SCHEMBL4362988 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2HIF1ATAAR1SLC6A2CPA1 | |
| SCHEMBL28243868 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2HIF1ATAAR1SLC6A2CPA1 | |
| SCHEMBL7797910 | 0.71 | TRPA1 (0.46) | SMN1; SMN2HIF1ATAAR1SLC6A2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9849196-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2017-12-26 | — | — | US | disclosed |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2015-11-19 | — | — | US | disclosed |
| US-8945515-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2015-02-03 | — | — | US | disclosed |
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2010096720-A2 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, PPOX, PRDX5 | SMN1; SMN2 3773/4885HIF1A 381/4885TAAR1 2500/4885 |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, ARFGEF1, PRDX3 | SMN1; SMN2 3645/4885HIF1A 585/4885TAAR1 1823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.