Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522054 | 0.83 | FFAR1 (0.52) | CA12CA9TSHRMEN1KMT2A | |
| SCHEMBL812702 | 0.81 | CA12 (0.78) | NR1I2CA12CA9TSHRNR1H3 | |
| SCHEMBL7354826 | 0.77 | CA12 (0.35) | NR1I2CA12CA9TSHRL3MBTL1 | |
| SCHEMBL22792328 | 0.77 | L3MBTL1 (0.56) | NR1I2CA12CA9NR1H3NR1H2 | |
| SCHEMBL9959448 | 0.76 | CA12 (0.56) | NR1I2CA12CA9TSHRNR1H3 | |
| SCHEMBL3398530 | 0.75 | NR1H2 (0.55) | NR1I2NR1H3NR1H2MAPT | |
| SCHEMBL11910521 | 0.74 | CA12 (0.86) | NR1I2CA12CA9NR1H3NR1H2 | |
| SCHEMBL6301401 | 0.73 | NPC1 (0.67) | NR1I2CA12CA9TSHRNR1H3 | |
| SCHEMBL2690068 | 0.73 | NR1I2 (0.61) | NR1I2CA12CA9TSHRNR1H3 | |
| SCHEMBL10186889 | 0.73 | PGR (0.74) | NR1I2CA12CA9NR1H3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973884-A2 | NOVEL HETEROCYCLES | Orchid Research Laboratories Limited (IN) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007083182-A2 | NOVEL HETEROCYCLES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-07-26 | — | — | WO | disclosed |