Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842044 | 0.79 | QTRT1 (0.51) | KDM4EGPR3TOP2AGABRA1GABRG2 | |
| SCHEMBL311958 | 0.79 | PARP1 (0.51) | KDM4EGPR3TOP2ANPC1ALDH1A1 | |
| SCHEMBL311168 | 0.79 | KDM4E (0.46) | KDM4EGPR3TOP2AGABRA1GABRG2 | |
| SCHEMBL1486423 | 0.77 | KDM4E (0.44) | KDM4EGPR3TOP2AGABRA1GABRG2 | |
| SCHEMBL1423662 | 0.76 | TNKS (0.56) | TOP2ANPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL2088588 | 0.75 | ERN1 (0.45) | KDM4EGPR3TOP2AGABRA1GABRG2 | |
| SCHEMBL5338042 | 0.75 | KDM4E (0.42) | KDM4EGPR3TOP2AHDAC6RAB9A | |
| SCHEMBL9603222 | 0.75 | PKM (0.55) | KDM4EGPR3TOP2AGABRA1GABRG2 | |
| SCHEMBL203874 | 0.75 | MAPK14 (0.42) | KDM4EGPR3TOP2AALDH1A1HPGD | |
| SCHEMBL5341134 | 0.75 | LOXL2 (0.42) | KDM4EGPR3TOP2AGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948173-A2 | HYDROXY AND ALKOXY SUBSTITUTED 1H-IMIDAZOQUINOLINES AND METHODS | Coley Pharmaceutical Group, Inc. (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007056112-A2 | HYDROXY AND ALKOXY SUBSTITUTED 1H-IMIDAZOQUINOLINES AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-05-18 | — | — | WO | disclosed |