Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535358 | 0.65 | SLC6A4 (0.46) | SLC6A4SLC6A2HTR1B | |
| SCHEMBL5318577 | 0.65 | SLC6A4 (0.46) | SLC6A4SLC6A2HTR1B | |
| SCHEMBL5481115 | 0.64 | ALDH1A1 (0.54) | SLC6A4HTR1BHPGD | |
| SCHEMBL2561039 | 0.64 | HTR1B (0.44) | SLC6A4SLC6A2HTR1BHPGD | |
| Hydrochloric Acid SCHEMBL4053969 | 0.64 | SLC6A4 (0.45) | SLC6A4SLC6A2HTR1B | |
| SCHEMBL9613977 | 0.63 | LTB4R (0.37) | HPGD | |
| SCHEMBL4971364 | 0.62 | HTR1B (0.42) | SLC6A4SLC6A2HTR1B | |
| SCHEMBL5120304 | 0.60 | TAAR1 (0.39) | — | |
| SCHEMBL4258447 | 0.60 | TAAR1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL4730956 | 0.59 | SMN1; SMN2 (0.39) | SLC6A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133884-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-11-06 | — | — | WO | disclosed |