Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16673587 | 0.83 | FAAH (0.71) | FAAHMEN1KMT2AMGLLKDM4E | |
| SCHEMBL5382195 | 0.77 | FAAH (0.72) | FAAHMEN1KMT2AMGLLKDM4E | |
| SCHEMBL3088484 | 0.72 | MPO (0.73) | FAAHMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14939397 | 0.72 | ALDH1A1 (0.54) | FAAHMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL211923 | 0.71 | FAAH (0.72) | FAAHMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3098473 | 0.71 | ALDH1A1 (0.70) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL2931693 | 0.71 | FAAH (0.70) | FAAHMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2930821 | 0.70 | HTT (0.57) | FAAHMEN1KMT2AMGLLKDM4E | |
| SCHEMBL28648421 | 0.70 | HRH3 (0.51) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL2931365 | 0.70 | ALDH1A1 (0.53) | FAAHMEN1KMT2AMGLLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963315-A2 | ENZYME INHIBITORS | The Institute of Cancer Research (GB) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072017-A2 | ENZYME INHIBITORS | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-06-28 | — | — | WO | disclosed |