Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3098473 | 0.85 | ALDH1A1 (0.70) | ALDH1A1KDM4EPOLBLMNAKMT2A | |
| SCHEMBL3088484 | 0.83 | MPO (0.73) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL2931693 | 0.82 | FAAH (0.70) | ALDH1A1KDM4EPOLBLMNAKMT2A | |
| SCHEMBL23293594 | 0.81 | HTR7 (0.63) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL16673587 | 0.80 | FAAH (0.71) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL2850013 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL13469106 | 0.79 | MC4R (0.58) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL28648421 | 0.78 | HRH3 (0.51) | ALDH1A1KDM4EPOLBLMNAKMT2A | |
| SCHEMBL2930821 | 0.78 | HTT (0.57) | ALDH1A1KDM4EPOLBLMNAKMT2A | |
| SCHEMBL2938460 | 0.78 | KDM4E (0.74) | ALDH1A1KDM4EPOLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |