Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769435 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HPGDATAD2CECR2GRM4 | |
| SCHEMBL4518635 | 0.65 | HPGD (0.41) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL109045 | 0.65 | ALDH1A1 (0.54) | ALDH1A1HPGDKMT2AMEN1TP53 | |
| SCHEMBL5929414 | 0.65 | ALDH1A1 (0.46) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL6249309 | 0.64 | KDM4E (0.33) | ALDH1A1TP53 | |
| SCHEMBL10076741 | 0.64 | L3MBTL1 (0.45) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL1232653 | 0.63 | MAPK1 (0.38) | ALDH1A1KMT2AMEN1TP53MAPT | |
| Hydrochloric Acid SCHEMBL21800936 | 0.63 | GRM4 (0.39) | ALDH1A1GRM4KMT2AMEN1MAPT | |
| SCHEMBL21765862 | 0.62 | MEN1 (0.54) | ALDH1A1KMT2AMEN1TP53MAPT | |
| SCHEMBL12410094 | 0.60 | ALDH1A1 (0.59) | ALDH1A1HPGDATAD2CECR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403900-B2 | Anti-human respiratory syncytial virus (RSV) antibodies and methods of use | CRUCELL HOLLAND B.V. (NL) | 2016-08-02 | — | — | US | disclosed |
| US-9297006-B2 | Methods of nucleic acid amplification and sequencing | ILLUMINA, INC. (US) | 2016-03-29 | — | — | US | disclosed |
| EP-2080525-B1 | Remodeling and glycoconjugation of poly(ether) to erythropietin | RATIOPHARM GMBH (DE) | 2015-12-16 | — | — | EP | disclosed |
| US-20140363427-A1 | ANTI-HUMAN RESPIRATORY SYNCYTIAL VIRUS (RSV) ANTIBODIES AND METHODS OF USE | CALMUNE CORPORATION | 2014-12-11 | — | — | US | disclosed |
| US-20140228254-A1 | Methods of Nucleic acid amplification and sequencing | ILLUMINA, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-8652810-B2 | Methods of nucleic acid amplification and sequencing | ILLUMINA, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| US-20080160580-A1 | Methods of nucleic acid amplification and sequencing | SOLEXA, INC | 2008-07-03 | — | — | US | disclosed |
| US-7115400-B1 | Methods of nucleic acid amplification and sequencing | SOLEXA LTD. (GB) | 2006-10-03 | — | — | US | disclosed |