Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43927 | 0.87 | KDM4E (0.40) | ALDH1A1ALOX12KDM4EGRM4MEN1 | |
| SCHEMBL27471377 | 0.82 | MYC (0.51) | ALDH1A1KDM4EGRM4TP53POLB | |
| Hydrochloric Acid SCHEMBL21800936 | 0.79 | GRM4 (0.39) | ALDH1A1KDM4EGRM4MEN1KMT2A | |
| SCHEMBL567033 | 0.76 | KDM4E (0.38) | ALDH1A1KDM4EGRM4MEN1KMT2A | |
| SCHEMBL9596295 | 0.76 | CA12 (0.39) | ALDH1A1KDM4EKMT2AMAPTTP53 | |
| SCHEMBL22344998 | 0.75 | CHRM1 (0.35) | ALDH1A1ALOX12CHRM1KDM4EKDM4C | |
| SCHEMBL6887707 | 0.72 | CA12 (0.48) | ALDH1A1KMT2ATP53POLBHSD17B10 | |
| SCHEMBL317703 | 0.71 | KEAP1 (0.43) | ALDH1A1KDM4EMEN1KMT2ATP53 | |
| SCHEMBL31653832 | 0.71 | KEAP1 (0.43) | ALDH1A1KDM4EMEN1KMT2ATP53 | |
| SCHEMBL317626 | 0.71 | CA12 (0.42) | KDM4EGRM4KMT2ATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587639-B1 | PHARMACEUTICAL COMPOSITIONS | LIPOXEN LTD (GB) | 2001-08-16 | — | — | EP | disclosed |
| US-5846951-A | Pharmaceutical compositions | THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 1998-12-08 | — | — | US | disclosed |
| EP-0587639-A1 | PHARMACEUTICAL COMPOSITIONS | THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 1994-03-23 | — | — | EP | disclosed |
| WO-1992022331-A1 | PHARMACEUTICAL COMPOSITIONS | THE SCHOOL OF PHARMACY (GB) | 1992-12-23 | — | — | WO | disclosed |