SCHEMBL5138087

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25822610	0.78	NPC1 (0.36)	TDO2KDM4EHSD17B10TP53MAPT
	SCHEMBL5138250	0.78	NPC1 (0.51)	KDM4EHSD17B10TP53MAPTPKM
	SCHEMBL5139212	0.77	DYRK1A (0.40)	KDM4EHSD17B10TP53PKMSMN1; SMN2
	SCHEMBL5985411	0.76	TDO2 (0.52)	TDO2KDM4EPIM1NPC1TGFBR1
	SCHEMBL5202666	0.76	MAP3K11 (0.46)	NPC1DYRK2LRRK2
	SCHEMBL23418360	0.75	NPC1 (0.36)	TDO2KDM4ESMN1; SMN2PIM1NPC1
	SCHEMBL25822607	0.75	NPC1 (0.42)	KDM4EHSD17B10TP53MAPTPKM
	SCHEMBL5697021	0.75	DYRK1A (0.40)	KDM4EHSD17B10TP53MAPTPKM
	SCHEMBL5138443	0.75	TGFBR1 (0.46)	KDM4EMAPTPKMSMN1; SMN2LMNA
	SCHEMBL27628474	0.74	TGFBR1 (0.49)	KDM4ETP53PKMSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.