SCHEMBL5138997

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5138429	0.88	MEN1 (0.50)	PIM1ALDH1A1SMN1; SMN2HPGDMAPT
	SCHEMBL5139037	0.87	MEN1 (0.39)	PIM1ALDH1A1SMN1; SMN2HPGDMAPT
	SCHEMBL5200816	0.85	IP6K1 (0.37)	PIM1ALDH1A1SMN1; SMN2HPGDMAPT
	SCHEMBL5138199	0.83	SMN1; SMN2 (0.48)	ALDH1A1SMN1; SMN2HPGDMEN1KMT2A
	SCHEMBL8489109	0.80	L3MBTL1 (0.44)	SMN1; SMN2KDM4EPOLBLMNATGFBR1
	SCHEMBL5930941	0.80	TGFBR1 (0.38)	ALDH1A1SMN1; SMN2HPGDKDM4EPOLB
	SCHEMBL6178618	0.79	TGFBR1 (0.59)	TGFBR1GRM5
	SCHEMBL5188130	0.79	GRM5 (0.46)	SMN1; SMN2MAPTMEN1KMT2ATSHR
	SCHEMBL5138712	0.77	ALDH1A1 (0.43)	ALDH1A1SMN1; SMN2HPGDKDM4EPOLB
	SCHEMBL3854762	0.76	MEN1 (0.52)	ALDH1A1SMN1; SMN2HPGDMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.