Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046700 | 0.90 | LMNA (0.61) | LMNAL3MBTL1TP53CNR1TACR3 | |
| SCHEMBL4449047 | 0.83 | LMNA (0.69) | LMNAL3MBTL1TP53TACR3PDE10A | |
| SCHEMBL5045993 | 0.83 | LMNA (0.66) | LMNAL3MBTL1TP53CNR1TACR3 | |
| SCHEMBL5045806 | 0.83 | LMNA (0.66) | LMNAL3MBTL1TP53CNR1TACR3 | |
| SCHEMBL16553849 | 0.82 | LMNA (0.67) | LMNAL3MBTL1TP53CNR1TACR3 | |
| SCHEMBL3870523 | 0.81 | LMNA (0.65) | LMNAL3MBTL1TP53CNR1TACR3 | |
| Hydrochloric Acid SCHEMBL5499021 | 0.80 | LMNA (0.64) | LMNAL3MBTL1TP53CNR1TACR3 | |
| SCHEMBL4438433 | 0.80 | LMNA (0.64) | LMNAL3MBTL1TP53CNR1TACR3 | |
| SCHEMBL5049768 | 0.79 | LMNA (0.63) | LMNAL3MBTL1TP53CNR1TACR3 | |
| SCHEMBL4667123 | 0.79 | LMNA (0.66) | LMNAL3MBTL1TP53CNR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928835-A1 | ALKYL SULFOXIDE QUINOLINES AS NK-3 RECEPTOR LIGANDS | Astra Zeneca AB (SE) | 2008-06-11 | — | — | EP | claimed |
| WO-2007035158-A1 | ALKYL SULFOXIDE QUINOLINES AS NK-3 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2007-03-29 | — | — | WO | claimed |