Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140765 | 0.82 | NPSR1 (0.50) | TDP1L3MBTL1ALDH1A1CA2NPSR1 | |
| SCHEMBL5035699 | 0.78 | TDP1 (0.64) | TDP1L3MBTL1ALDH1A1CA2NPSR1 | |
| SCHEMBL5035705 | 0.78 | TDP1 (0.64) | TDP1L3MBTL1ALDH1A1CA2NPSR1 | |
| SCHEMBL3092210 | 0.78 | DGAT1 (0.55) | TDP1L3MBTL1ALDH1A1NPSR1ITGB3 | |
| SCHEMBL3105657 | 0.75 | DGAT1 (0.53) | TDP1L3MBTL1ALDH1A1ITGB3ITGB1 | |
| SCHEMBL5036076 | 0.75 | CA2 (0.64) | TDP1L3MBTL1ALDH1A1CA2NPSR1 | |
| SCHEMBL1750558 | 0.75 | CA2 (0.64) | TDP1L3MBTL1ALDH1A1CA2NPSR1 | |
| SCHEMBL24313493 | 0.74 | ALDH1A1 (0.56) | TDP1L3MBTL1ALDH1A1CA2NPSR1 | |
| SCHEMBL3094864 | 0.74 | DGAT1 (0.58) | L3MBTL1ALDH1A1CA2NPSR1ITGB3 | |
| SCHEMBL3575901 | 0.73 | TDP1 (0.66) | TDP1L3MBTL1ALDH1A1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912634-A2 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | Bayer Healthcare, LLC (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2007016538-A2 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2007-02-08 | — | — | WO | claimed |