Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3094864 | 0.87 | DGAT1 (0.58) | NPSR1ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL3092210 | 0.84 | DGAT1 (0.55) | NPSR1ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL5140198 | 0.82 | TDP1 (0.47) | NPSR1ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL3103290 | 0.78 | DGAT1 (0.56) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL5036076 | 0.77 | CA2 (0.64) | NPSR1ALDH1A1CA2L3MBTL1DGAT1 | |
| SCHEMBL1750558 | 0.77 | CA2 (0.64) | NPSR1ALDH1A1CA2L3MBTL1DGAT1 | |
| SCHEMBL24313493 | 0.77 | ALDH1A1 (0.56) | NPSR1ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL3105657 | 0.75 | DGAT1 (0.53) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL3103397 | 0.75 | DGAT1 (0.57) | NPSR1ALDH1A1CA2L3MBTL1DGAT1 | |
| SCHEMBL5537767 | 0.74 | CA2 (0.75) | NPSR1ALDH1A1CA2L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912634-A2 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | Bayer Healthcare, LLC (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2007016538-A2 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2007-02-08 | — | — | WO | claimed |