Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140718 | 1.00 | ADRB2 (0.47) | ADRB2TRPV1CASRPDE4APDE4B | |
| SCHEMBL5037003 | 0.94 | ADRB2 (0.44) | ADRB2TRPV1CASRADRB3 | |
| SCHEMBL5037004 | 0.94 | ADRB2 (0.44) | ADRB2TRPV1CASRADRB3 | |
| SCHEMBL5563548 | 0.92 | ADRB2 (0.47) | ADRB2TRPV1CASRPDE4APDE4B | |
| SCHEMBL5563552 | 0.92 | ADRB2 (0.47) | ADRB2TRPV1CASRPDE4APDE4B | |
| SCHEMBL14204698 | 0.90 | ADRB2 (0.46) | ADRB2TRPV1CASRPDE4APDE4B | |
| SCHEMBL5034398 | 0.89 | ADRB3 (0.41) | ADRB2TRPV1ADRB3 | |
| SCHEMBL5034395 | 0.89 | ADRB3 (0.41) | ADRB2TRPV1ADRB3 | |
| SCHEMBL2962080 | 0.88 | ADRB2 (0.48) | ADRB2TRPV1CASRPDE4APDE4B | |
| SCHEMBL2962085 | 0.88 | ADRB2 (0.48) | ADRB2TRPV1CASRPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351742-B2 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC. (US) | 2008-04-01 | — | — | US | disclosed |
| US-20050171147-A1 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC. | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171147-A1 | Sulfonamide derivatives for the treatment of diseases | SULT2A1, STS, SULT1A1 | ADRB2 2148/4885TRPV1 88/4885CASR 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.