Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3098659 | 0.84 | MMP12 (0.58) | POLBTRPA1CNR2CES2CES1 | |
| SCHEMBL3085039 | 0.80 | TRPA1 (0.69) | TRPA1CES2CES1AKR1B1TRPV1 | |
| SCHEMBL21944189 | 0.80 | TSHR (0.53) | POLBTRPA1CNR2CES2CES1 | |
| SCHEMBL106992 | 0.76 | TSHR (0.53) | POLBCNR2CES2CES1AKR1B1 | |
| SCHEMBL18196797 | 0.76 | ALDH1A1 (0.53) | TDP1L3MBTL1TSHRDPP4MMP9 | |
| SCHEMBL8862339 | 0.76 | ALDH1A1 (0.53) | TDP1L3MBTL1TSHRDPP4MMP9 | |
| SCHEMBL15156248 | 0.75 | POLB (0.54) | POLBCNR2CES2CES1AKR1B1 | |
| SCHEMBL108380 | 0.75 | TSHR (0.49) | POLBTRPA1CNR2CES2CES1 | |
| SCHEMBL10420359 | 0.75 | DPP4 (0.55) | POLBTRPA1CES2CES1TDP1 | |
| SCHEMBL21908588 | 0.75 | TSHR (0.45) | POLBCNR2CES2CES1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326797-B2 | Manufacture of isoflavones | DSM IP ASSETS B.V. (NL) | 2008-02-05 | — | — | US | disclosed |
| CN-100363357-C | Preparation of isoflavones | DSM IP ASSETS BV (NL) | 2008-01-23 | — | — | CN | disclosed |
| EP-1523478-B1 | MANUFACTURE OF ISOFLAVONES | DSM IP ASSETS BV (NL) | 2007-12-12 | — | — | EP | disclosed |
| US-20050256321-A1 | Manufacture of isoflavones | DSM IP ASSETS B.V. (NL) | 2005-11-17 | — | — | US | disclosed |
| CN-1684950-A | Preparation of isoflavones | DSM IP ASSETS BV (NL) | 2005-10-19 | — | — | CN | disclosed |
| EP-1523478-A2 | MANUFACTURE OF ISOFLAVONES | DSM IP Assets B.V. (NL) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004009576-A2 | MANUFACTURE OF ISOFLAVONES | DSM IP ASSETS B.V. (NL) | 2004-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256321-A1 | Manufacture of isoflavones | HAAO, HAO2, CYP2F1 | POLB 2555/4885TRPA1 4510/4885CNR2 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.