Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341585 | 0.83 | CES2 (0.60) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL8962890 | 0.80 | CES2 (0.57) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL6831436 | 0.76 | CES2 (0.55) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL8976663 | 0.75 | L3MBTL1 (0.47) | CES2CES1ALDH1A1TSHRMEN1 | |
| SCHEMBL8107324 | 0.74 | ALDH1A1 (0.74) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL8124407 | 0.72 | ALDH1A1 (0.58) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL8976660 | 0.72 | ALDH1A1 (0.53) | ALDH1A1TSHRSMN1; SMN2MAPTHTT | |
| SCHEMBL9079084 | 0.71 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTHTTRAB9A | |
| SCHEMBL10903202 | 0.71 | ALDH1A1 (0.56) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL7651789 | 0.71 | SNCA (0.44) | MEN1KMT2AMAPTHSP90AA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001896-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | Agilent Technologies, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| WO-2007112263-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | AGILENT TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | WO | claimed |