SCHEMBL5142183

SCHEMBL5142183

C=Cc1ccc(CC(C(=O)O)(C(=O)O)C(C)(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 2/20 0.40
ALDH1A1 P00352 5/20 0.40
CYP3A4 P08684 3/20 0.40
CYP2C19 P33261 2/20 0.40
CYP2C9 P11712 2/20 0.40
ESR1 P03372 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
LMNA P02545 2/20 0.35
PSMD14 O00487 1/20 0.35
TDP1 Q9NUW8 3/20 0.34
PPARA Q07869 5/20 0.34
KDM4E B2RXH2 2/20 0.34
CYP1A2 P05177 2/20 0.34
POLB P06746 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
ALOX15 P16050 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7724203 0.80 ALDH1A1 (0.42) THRATHRBALDH1A1CYP3A4CYP2C19
SCHEMBL6567845 0.79 BLM (0.62) THRATHRBBLMALDH1A1CYP3A4
SCHEMBL5360398 0.78 SMN1; SMN2 (0.53) BLMALDH1A1CYP3A4CYP2C19CYP2C9
SCHEMBL1611980 0.78 THRA (0.53) THRATHRBALDH1A1CYP3A4CYP2C19
SCHEMBL5144303 0.78 THRA (0.44) THRATHRBBLMALDH1A1CYP3A4
SCHEMBL21269112 0.77 HIF1A (0.52) BLMALDH1A1CYP3A4CYP2C19CYP2C9
SCHEMBL28314481 0.77 HIF1A (0.52) BLMALDH1A1CYP3A4CYP2C19CYP2C9
SCHEMBL21269875 0.77 HIF1A (0.52) BLMALDH1A1CYP3A4CYP2C19CYP2C9
SCHEMBL21269695 0.77 HIF1A (0.52) BLMALDH1A1CYP3A4CYP2C19CYP2C9
SCHEMBL28314407 0.77 HIF1A (0.52) BLMALDH1A1CYP3A4CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1240552-B1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS INTELLECTUAL VENTURES HOLDING 40 LLC (US) 2012-09-19 EP disclosed
EP-1240552-A4 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS UNIV TEXAS (US) 2007-10-17 EP disclosed
EP-1240552-A1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS Board of Regents, The University of Texas System (US) 2002-09-18 EP disclosed
US-6399273-B1 Water-processable photoresist compositions BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM 2002-06-04 US disclosed
WO-2001013179-A1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) 2001-02-22 WO disclosed