SCHEMBL514289

SCHEMBL514289

CSc1ccc(I)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24177553 0.92 PTGS2 (0.45)
SCHEMBL16705627 0.85 CYP1A1 (0.44)
SCHEMBL83839 0.83 ALDH1A1 (0.58)
SCHEMBL24177551 0.82 PLK1 (0.52)
SCHEMBL16995426 0.82 TSHR (0.50)
SCHEMBL26106467 0.79 ALDH1A1 (0.55)
SCHEMBL23051049 0.78 ALDH1A1 (0.40)
SCHEMBL21625401 0.75 ALDH1A1 (0.46)
SCHEMBL222988 0.73 HSD17B10 (0.44)
SCHEMBL5887631 0.73 CYP3A4 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371674-A Preparation method of donor-acceptor type metal organic framework photocatalyst and application of photocatalytic amine oxide/thioether 长沙理工大学 2025-01-28 CN claimed
US-20250264649-A1 HIGH REFRACTIVE INDEX AND HIGHLY BIREFRINGENT SOLID ORGANIC MATERIALS META PLATFORMS TECH LLC (US) 2025-08-21 US disclosed
US-12320999-B2 High refractive index and highly birefringent solid organic materials META PLATFORMS TECHNOLOGIES, LLC (US) 2025-06-03 US disclosed
US-20240425504-A1 IMIDAZOPYRIDINONE COMPOUND KISSEI PHARMACEUTICAL CO., LTD. (assignee) (JP) 2024-12-26 US disclosed
EP-3808747-B1 IMIDAZOPYRIDINONE COMPOUND KISSEI PHARMACEUTICAL (JP) 2024-12-18 EP disclosed
EP-4455126-A1 LIGHT-MEDIATED AEROBIC OXIDATION METHOD Ecosynth (BE) 2024-10-30 EP disclosed
US-12077531-B2 Imidazopyridinone compound KISSEI PHARMACEUTICAL CO., LTD. (JP) 2024-09-03 US disclosed
CN-118373784-B One-pot preparation method of 2-aryl benzoxazole and asymmetric sulfoxide 江苏师范大学 2024-09-03 CN disclosed
WO-2024165619-A1 LIGHT-MEDIATED AEROBIC OXIDATION METHOD HG HOLDING B.V. (NL) 2024-08-15 WO disclosed
CN-118373784-A One-pot preparation method of 2-aryl benzoxazole and asymmetric sulfoxide 江苏师范大学 2024-07-23 CN disclosed
WO-1995024400-A1 THIAZOLIDINEDIONE DERIVATIVES AS ANTI-HYPERGLYCEMIC AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1995-09-14 WO disclosed
US-5317019-A Antiinflammatory agents SMITHKLINE BEECHAM CORP. (US) 1994-05-31 US disclosed
US-5145858-A Antiinflammatory SMITHKLINE BEECHAM CORP. (US) 1992-09-08 US disclosed
US-5002941-A Antiarthritic agents, arachidonic acid metabolism SMITHKLINE BEECHAM CORPORATION (US) 1991-03-26 US disclosed
EP-0411754-A2 Medicament for the inhibition of interleukin-1 or tumor necrosis factor production by monocytes and/or macrophages SMITHKLINE BEECHAM CORPORATION (US) 1991-02-06 EP disclosed
WO-1991000092-A1 INHIBITION OF INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR PRODUCTION BY MONOCYTES AND/OR MACROPHAGES SMITHKLINE BEECHAM CORPORATION (US) 1991-01-10 WO disclosed
WO-1990003789-A1 PYRROLO[1,2-a]IMIDAZOLE AND IMIDAZO[1,2-a]PYRIDINE DERIVATIVES AND THEIR USE AS 5-LYPOXYGENASE PATHWAY INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1990-04-19 WO disclosed
EP-0364204-A1 Pyrrolo[1,2-a]imidazole and imidazo[1,2-a]pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors SMITHKLINE BEECHAM CORPORATION (US) 1990-04-18 EP disclosed
EP-0306300-A2 Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors SMITHKLINE BEECHAM CORPORATION (US) 1989-03-08 EP disclosed
US-4087549-A Sulphonic acid containing indenyl derivatives MERCK & CO., INC. (US) 1978-05-02 US disclosed