Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.44 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL28988939 | 0.89 | MAPK1 (0.60) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL17125509 | 0.88 | NOTUM (0.62) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL27250 | 0.87 | NOTUM (0.65) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL4341894 | 0.87 | NOTUM (0.78) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL18473284 | 0.85 | NOTUM (0.47) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL6428811 | 0.85 | NOTUM (0.63) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL28493417 | 0.85 | NOTUM (0.63) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL15510676 | 0.85 | NOTUM (0.63) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL842039 | 0.85 | NOTUM (0.63) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL514704 | 0.85 | NOTUM (0.63) | NOTUMMAPK1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1218472-A | Pharmaceutically useful compounds | ASTRA PHARMA PROD (GB) | 1999-06-02 | — | — | CN | claimed |
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2023-06-01 | — | — | US | disclosed |
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2023-06-01 | — | — | US | disclosed |
| US-11584720-B2 | Photoredox-catalyzed direct C-H functionalization of arenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-02-21 | — | — | US | disclosed |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | UNIV SOUTHERN CALIFORNIA (US) | 2020-12-10 | — | — | US | disclosed |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | UNIV SOUTHERN CALIFORNIA (US) | 2020-12-10 | — | — | US | disclosed |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2020-08-11 | — | — | US | disclosed |
| EP-3109238-B1 | PHENYL-PYRAZOLE COMPLEXES OF IRIDIUM | UNIV SOUTHERN CALIFORNIA (US) | 2019-09-18 | — | — | EP | disclosed |
| US-10399947-B2 | Photoredox-catalyzed direct C—H functionalization of arenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180148414-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2018-05-31 | — | — | US | disclosed |
| EP-1606296-B1 | PHENYL-PYRAZOLE COMPLEXES OF Ir | UNIV SOUTHERN CALIFORNIA (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-2062908-A1 | Complexes of iridium comprising pyrazolylcarbazole ligands | University of Southern California (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-2043970-A2 | IRON-COPPER CO-CATALYZED PROCESS FOR CARBON-CARBON OR CARBON-HETEROATOM BONDING | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-04-08 | — | — | EP | disclosed |
| US-20080176102-A1 | Organic light emitting devices; electroluminescent efficiency, durability; such as tris(1-(4-biphenyl)pyrazolato)iridium complexes | THOMPSON MARK E | 2008-07-24 | — | — | US | disclosed |
| US-7338722-B2 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-03-04 | — | — | US | disclosed |
| WO-2008004088-A2 | IRON-COPPER CO-CATALYZED PROCESS FOR CARBON-CARBON OR CARBON-HETEROATOM BONDING | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-01-10 | — | — | WO | disclosed |
| WO-2008004088-A2 | IRON-COPPER CO-CATALYZED PROCESS FOR CARBON-CARBON OR CARBON-HETEROATOM BONDING | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-01-10 | — | — | WO | disclosed |
| EP-1606296-A2 | PHENYL-PYRAZOLE COMPLEXES OF Ir | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-12-21 | — | — | EP | disclosed |
| US-20040253478-A1 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | UNIVERSITY OF SOUTHERN CALIFORNIA, THE | 2004-12-16 | — | — | US | disclosed |
| WO-2004085450-A2 | PHENYL-PYRAZOLE COMPLEXES OF IR | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584720-B2 | Photoredox-catalyzed direct C-H functionalization of arenes | PPOX, AOC2, AOC3 | NOTUM 3331/4885MAPK1 3425/4885ALDH1A1 495/4885 |
| US-20040253478-A1 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | NR2E3, IK, NR2C2 | NOTUM 3367/4885MAPK1 3037/4885ALDH1A1 2031/4885 |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | EML4, RCOR3, CPNE4 | NOTUM 4244/4885MAPK1 3632/4885ALDH1A1 630/4885 |
| US-10399947-B2 | Photoredox-catalyzed direct C—H functionalization of arenes | PPOX, AOC2, AOC3 | NOTUM 3386/4885MAPK1 3469/4885ALDH1A1 511/4885 |
| US-20080176102-A1 | Organic light emitting devices; electroluminescent efficiency, durability; such as tris(1-(4-biphenyl)pyrazolato)iridium complexes | EML4, RNF4, LIG4 | NOTUM 3476/4885MAPK1 3568/4885ALDH1A1 413/4885 |
| US-20180148414-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | PPOX, AOC2, AOC3 | NOTUM 3331/4885MAPK1 3425/4885ALDH1A1 495/4885 |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | EML4, AFF4, RCOR3 | NOTUM 4245/4885MAPK1 3319/4885ALDH1A1 664/4885 |
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | PPOX, AOC2, AOC3 | NOTUM 3331/4885MAPK1 3425/4885ALDH1A1 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.