SCHEMBL514382

SCHEMBL514382

[CH2]S(=O)(=O)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.49
MMP2 P08253 2/20 0.46
MMP9 P14780 2/20 0.46
MMP14 P50281 2/20 0.46
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
KIF11 P52732 1/20 0.46
PTGS2 P35354 2/20 0.45
PTGS1 P23219 1/20 0.45
EPHX2 P34913 1/20 0.44
HTR2A P28223 1/20 0.43
NOD1 Q9Y239 1/20 0.42
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NR3C1 P04150 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
ABL1 P00519 1/20 0.41
BCR P11274 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13542559 0.81 FFAR4 (0.50) FFAR4MMP2MMP9MMP14BCHE
SCHEMBL514383 0.79 PTGS2 (0.65) FFAR4MMP2MMP9MMP14BCHE
SCHEMBL5333957 0.79 BCHE (0.50) FFAR4MMP2MMP9MMP14BCHE
SCHEMBL1137645 0.79 PTGS2 (0.65) FFAR4KIF11PTGS2PTGS1SLC6A4
SCHEMBL3176978 0.79 FFAR4 (0.49) FFAR4MMP2MMP9MMP14BCHE
SCHEMBL14875137 0.79 FFAR4 (0.49) FFAR4MMP2MMP9MMP14BCHE
SCHEMBL65853 0.79 FFAR4 (0.49) FFAR4MMP2MMP9MMP14BCHE
SCHEMBL2371770 0.79 FFAR4 (0.56) FFAR4MMP2MMP9MMP14BCHE
SCHEMBL2377118 0.79 MMP2 (0.54) FFAR4MMP2MMP9MMP14BCHE
SCHEMBL18637225 0.79 FFAR4 (0.45) FFAR4MMP2MMP9MMP14BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
WO-2014184070-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
WO-2014184071-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
EP-2420493-A1 HALOALKYLSULFONANILIDE DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE CBR3, CBR1, HDHD5 FFAR4 2918/4885MMP2 3744/4885MMP9 3035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.