Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144531 | 1.00 | LMNA (0.50) | LMNACA2TACR1ITGB3ITGA2B | |
| SCHEMBL3517991 | 0.91 | LMNA (0.46) | LMNACA2TACR1ITGB3ITGA2B | |
| SCHEMBL3517987 | 0.91 | LMNA (0.46) | LMNACA2TACR1ITGB3ITGA2B | |
| SCHEMBL23045324 | 0.84 | CA2 (0.43) | CA2FPR2ALDH1A1FTOFOLH1 | |
| SCHEMBL23045322 | 0.84 | CA2 (0.43) | CA2FPR2ALDH1A1FTOFOLH1 | |
| SCHEMBL604816 | 0.84 | CA2 (0.66) | LMNACA2TACR1ITGB3ITGA2B | |
| SCHEMBL607903 | 0.84 | CA2 (0.66) | LMNACA2TACR1ITGB3ITGA2B | |
| SCHEMBL468886 | 0.83 | SIRT5 (0.52) | LMNAITGB3ITGA2BKDM4EMAPT | |
| SCHEMBL468888 | 0.83 | SIRT5 (0.52) | LMNAITGB3ITGA2BKDM4EMAPT | |
| SCHEMBL4800632 | 0.81 | LMNA (0.45) | LMNACA2TACR1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1540341-A4 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | UNIV ROCHESTER MEDICAL CT (US) | 2007-01-10 | — | — | EP | claimed |
| US-20060166295-A1 | Method for determination of likelihood of occurrence of preterm labor in pregnant females | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-07-27 | — | — | US | claimed |
| EP-1540341-A1 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | The University of Rochester Medical Center (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004003555-A1 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | UNIVERSITY OF ROCHESTER MEDICAL CENTER (US) | 2004-01-08 | — | — | WO | claimed |
| EP-1540341-A4 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | UNIV ROCHESTER MEDICAL CT (US) | 2007-01-10 | — | — | EP | disclosed |
| US-20060166295-A1 | Method for determination of likelihood of occurrence of preterm labor in pregnant females | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-07-27 | — | — | US | disclosed |
| EP-1540341-A1 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | The University of Rochester Medical Center (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004003555-A1 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | UNIVERSITY OF ROCHESTER MEDICAL CENTER (US) | 2004-01-08 | — | — | WO | disclosed |