Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807907 | 0.87 | KMT2A (0.40) | LMNAHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL5144382 | 0.85 | RAB9A (0.35) | SMN1; SMN2LMNAPOLBGAAHPGD | |
| SCHEMBL878441 | 0.81 | BTN3A1 (0.43) | POLBALDH1A1PKM | |
| SCHEMBL15765574 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAPOLBGAAHPGD | |
| SCHEMBL29539956 | 0.74 | LMNA (0.56) | SMN1; SMN2LMNAPOLBGAAHPGD | |
| SCHEMBL6708631 | 0.74 | LMNA (0.42) | SMN1; SMN2LMNAGAAMEN1KMT2A | |
| SCHEMBL2472082 | 0.73 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNAPOLBGAAHPGD | |
| SCHEMBL30557968 | 0.73 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNAPOLBGAAHPGD | |
| SCHEMBL7806320 | 0.73 | RAB9A (0.34) | SMN1; SMN2LMNAPOLBGAAHPGD | |
| SCHEMBL858403 | 0.72 | BTN3A1 (0.40) | LMNAPOLBHPGDMAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551420-A4 | ARYL PHOSPHATE DERIVATIVES WITH SELECTIVE ACTIVITY AGAINST ADENOVIRUS AND HIV | PARKER HUGHES INST (US) | 2007-11-21 | — | — | EP | disclosed |
| EP-1551420-A1 | ARYL PHOSPHATE DERIVATIVES WITH SELECTIVE ACTIVITY AGAINST ADENOVIRUS AND HIV | Parker Hughes Institute (US) | 2005-07-13 | — | — | EP | disclosed |
| WO-2003105863-A1 | ARYL PHOSPHATE DERIVATIVES WITH SELECTIVE ACTIVITY AGAINST ADENOVIRUS AND HIV | PARKER HUGHES INSTITUTE (US) | 2003-12-24 | — | — | WO | disclosed |