SCHEMBL514530

SCHEMBL514530

C=CCCCCC(=O)OCCCC

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.59
DGKA P23743 2/20 0.58
ALDH1A1 P00352 3/20 0.58
LMNA P02545 1/20 0.58
HPGD P15428 1/20 0.52
ATM Q13315 1/20 0.50
MGLL Q99685 1/20 0.50
MAPT P10636 2/20 0.49
THRB P10828 1/20 0.49
CNR1 P21554 1/20 0.49
DNM1 Q05193 1/20 0.49
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
ABCC4 O15439 1/20 0.46
PAM P19021 2/20 0.44
HCAR2 Q8TDS4 1/20 0.44
NAAA Q02083 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12803469 0.98 TSHR (0.62) TSHRDGKAALDH1A1LMNAHPGD
SCHEMBL12803459 0.98 TSHR (0.62) TSHRDGKAALDH1A1LMNAHPGD
SCHEMBL12804186 0.98 TSHR (0.62) TSHRDGKAALDH1A1LMNAHPGD
SCHEMBL3123509 0.98 TSHR (0.62) TSHRDGKAALDH1A1LMNAHPGD
SCHEMBL515244 0.98 TSHR (0.62) TSHRDGKAALDH1A1LMNAHPGD
SCHEMBL3111539 0.98 TSHR (0.62) TSHRDGKAALDH1A1LMNAHPGD
SCHEMBL514084 0.98 TSHR (0.62) TSHRDGKAALDH1A1LMNAHPGD
SCHEMBL14763919 0.98 TSHR (0.62) TSHRDGKAALDH1A1LMNAHPGD
SCHEMBL858498 0.98 TSHR (0.62) TSHRDGKAALDH1A1LMNAHPGD
SCHEMBL3119938 0.95 TSHR (0.62) TSHRDGKAALDH1A1LMNAMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343095-A Synthesis method of tert-butyl 4-triethoxysilyl butyrate 杭州国瑞生物科技有限公司 2024-01-05 CN claimed
CN-117343095-A Synthesis method of tert-butyl 4-triethoxysilyl butyrate 杭州国瑞生物科技有限公司 2024-01-05 CN disclosed
CN-117343095-A Synthesis method of tert-butyl 4-triethoxysilyl butyrate 杭州国瑞生物科技有限公司 2024-01-05 CN disclosed
CN-102369173-B Method for producing high-purity terminal olefin compound KURARAY CO 2014-09-10 CN disclosed
US-8790424-B2 Copolymer and use thereof for improving the cold flow properties of middle distillate fuels BASF SE (DE) 2014-07-29 US disclosed
US-20140086960-A1 IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES OM PHARMA (CH) 2014-03-27 US disclosed
EP-2415740-B1 METHOD FOR PRODUCING HIGH-PURITY TERMINAL OLEFIN COMPOUND KURARAY CO (JP) 2013-12-25 EP disclosed
US-8609886-B2 Method for producing high purity terminal olefin compound KURARAY CO., LTD. (JP) 2013-12-17 US disclosed
US-20120247001-A1 COPOLYMER AND USE THEREOF FOR IMPROVING THE COLD FLOW PROPERTIES OF MIDDLE DISTILLATE FUELS BASF SE (DE) 2012-10-04 US disclosed
US-20120178721-A1 IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES OM PHARMA (CH) 2012-07-12 US disclosed
WO-2007102081-A2 IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES OM PHARMA (CH) 2007-09-13 WO disclosed
CN-100335509-C Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2007-09-05 CN disclosed
EP-1734061-A2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof MITSUI CHEMICALS, INC. (JP) 2006-12-20 EP disclosed
CN-1737017-A Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2006-02-22 CN disclosed
CN-1737016-A Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2006-02-22 CN disclosed
CN-1219800-C Polar group-containing olefin copolymer, thermoplastic resin composition containing the same, and use thereof MITSUI CHEMICALS INC (JP) 2005-09-21 CN disclosed
US-20040122192-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. 2004-06-24 US disclosed
US-20020156207-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2002-10-24 US disclosed
CN-1342715-A Polar group-containing olefin copolymer, process for producing the same, thermoplastic resin composition containing the same, and use thereof MITSUI CHEMICALS INC (JP) 2002-04-03 CN disclosed
EP-1186619-A2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof Mitsui Chemicals, Inc. (JP) 2002-03-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140086960-A1 IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES HRH4, HRH2, IFNG TSHR 3006/4885DGKA 3130/4885ALDH1A1 718/4885
US-20120178721-A1 IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES HRH4, IFNG, HRH2 TSHR 2888/4885DGKA 3214/4885ALDH1A1 762/4885
US-20120247001-A1 COPOLYMER AND USE THEREOF FOR IMPROVING THE COLD FLOW PROPERTIES OF MIDDLE DISTILLATE FUELS ADH1A, ADH5, ADH1C TSHR 4405/4885DGKA 337/4885ALDH1A1 274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.