SCHEMBL5145301

SCHEMBL5145301

O=C(Nc1cc(C=Cc2ccc(C(F)(F)F)cc2)ccc1C(=O)O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.59
TRPM8 Q7Z2W7 1/20 0.59
MPO P05164 1/20 0.54
KMT2A Q03164 2/20 0.54
GRIK1 P39086 2/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
PKM P14618 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ACLY P53396 1/20 0.53
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
HDAC2 Q92769 1/20 0.51
PPARG P37231 1/20 0.51
PPARD Q03181 1/20 0.51
PPARA Q07869 1/20 0.51
NR1H4 Q96RI1 1/20 0.51
KCNK2 O95069 3/20 0.50
KCNK10 P57789 3/20 0.50
SNCA P37840 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5145298 1.00 TRPA1 (0.59) TRPA1TRPM8MPOKMT2AGRIK1
SCHEMBL27716751 0.96 TRPA1 (0.58) TRPA1TRPM8MPOKMT2AGRIK1
SCHEMBL28771390 0.91 LMNA (0.56) TRPA1TRPM8MPOKMT2AGRIK1
SCHEMBL14428444 0.90 NPC1 (0.50) TRPA1TRPM8MPOKMT2AGRIK1
SCHEMBL2276655 0.90 PKM (0.62) KMT2AGRIK1MEN1MAPTPKM
SCHEMBL2276651 0.90 PKM (0.62) KMT2AGRIK1MEN1MAPTPKM
SCHEMBL2276918 0.87 SNCA (0.66) TRPA1KMT2AGRIK1MEN1MAPT
SCHEMBL2276923 0.87 SNCA (0.66) TRPA1KMT2AGRIK1MEN1MAPT
SCHEMBL2272483 0.86 IGF2BP2 (0.57) KMT2AGRIK1MEN1MAPTPKM
SCHEMBL2272471 0.86 IGF2BP2 (0.57) KMT2AGRIK1MEN1MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed