SCHEMBL5146128

SCHEMBL5146128

O=S(=O)(c1[c]cccc1)c1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.45
AKR1B1 P15121 1/20 0.41
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NFE2L2 Q16236 9/20 0.36
PGR P06401 1/20 0.34
ABCC9 O60706 1/20 0.34
ABCC8 Q09428 1/20 0.34
KCNJ11 Q14654 1/20 0.34
KCNJ8 Q15842 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9498749 0.83 AKR1B1 (0.42) HSD11B1AKR1B1TSHRALDH1A1
SCHEMBL10438584 0.80 AKR1B1 (0.45) AKR1B1GAATSHR
SCHEMBL150811 0.80 HTR6 (0.38) GAA
SCHEMBL6295690 0.79 KMT2A (0.33) GAA
SCHEMBL5144369 0.78 KDM4E (0.41) HSD11B1GAAALDH1A1L3MBTL1ABCC9
SCHEMBL11692931 0.78 MYC (0.36) GAATSHRL3MBTL1
SCHEMBL9495334 0.78 AKR1B1 (0.41) HSD11B1AKR1B1ALDH1A1L3MBTL1NFE2L2
SCHEMBL248010 0.77 HSD11B1 (0.59) HSD11B1AKR1B1GAATSHRHSD17B10
SCHEMBL30697126 0.77 HSD11B1 (0.59) HSD11B1AKR1B1GAATSHRHSD17B10
SCHEMBL2123876 0.77 HSD11B1 (0.59) HSD11B1AKR1B1GAATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288360-B2 Image recording material FUJIFILM CORPORATION (JP) 2007-10-30 US disclosed
US-20040214104-A1 Image recording material FUJI PHOTO FILM CO., LTD. 2004-10-28 US disclosed
EP-0351332-B1 HERBICIDAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM RHONE-POULENC AGROCHIMIE (FR) 1993-03-24 EP disclosed
EP-0351332-A1 Herbicidal compounds and compositions containing them RHONE-POULENC AGROCHIMIE (FR) 1990-01-17 EP disclosed