Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | ITGA1 | P56199 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10438584 | 0.84 | AKR1B1 (0.45) | AKR1B1MEN1KMT2ATSHR | |
| SCHEMBL5146128 | 0.83 | HSD11B1 (0.45) | AKR1B1HSD11B1ALDH1A1TSHR | |
| SCHEMBL9482319 | 0.81 | MCL1 (0.42) | HSD11B1ALDH1A1MEN1LMNAMAPT | |
| SCHEMBL11490322 | 0.78 | KIF18A (0.36) | KIF18A | |
| SCHEMBL6335085 | 0.76 | AKR1B1 (0.56) | AKR1B1HSD11B1TRPV4ITGA1ALDH1A1 | |
| SCHEMBL29001803 | 0.76 | ALDH1A1 (0.54) | KIF18AHSD11B1ALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL11256201 | 0.74 | AKR1B1 (0.54) | AKR1B1HSD11B1TRPV4ITGA1ALDH1A1 | |
| SCHEMBL150811 | 0.74 | HTR6 (0.38) | MEN1KMT2A | |
| SCHEMBL2462163 | 0.74 | KIF18A (0.61) | AKR1B1KIF18AHSD11B1TRPV4ITGA1 | |
| SCHEMBL28243733 | 0.72 | MAPT (0.43) | HSD11B1ALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351332-B1 | HERBICIDAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM | RHONE-POULENC AGROCHIMIE (FR) | 1993-03-24 | — | — | EP | disclosed |
| EP-0351332-A1 | Herbicidal compounds and compositions containing them | RHONE-POULENC AGROCHIMIE (FR) | 1990-01-17 | — | — | EP | disclosed |