Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150811 | 0.80 | HTR6 (0.38) | KMT2AMEN1 | |
| SCHEMBL6295690 | 0.79 | KMT2A (0.33) | KMT2AMEN1 | |
| SCHEMBL5146128 | 0.78 | HSD11B1 (0.45) | AKR1B1HSD11B1NFE2L2ABCC9ABCC8 | |
| SCHEMBL11692931 | 0.78 | MYC (0.36) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL5144369 | 0.78 | KDM4E (0.41) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL2124755 | 0.77 | AKR1B1 (0.53) | AKR1B1HSD11B1KMT2AHTR2CHTR2B | |
| SCHEMBL250919 | 0.77 | AKR1B1 (0.53) | AKR1B1HSD11B1KMT2AHTR2CHTR2B | |
| SCHEMBL30333632 | 0.77 | AKR1B1 (0.53) | AKR1B1HSD11B1KMT2AHTR2CHTR2B | |
| SCHEMBL11048003 | 0.76 | HTR6 (0.40) | KMT2AMEN1 | |
| SCHEMBL10438578 | 0.74 | PTGS2 (0.40) | AKR1B1HSD11B1KMT2ANFE2L2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351332-B1 | HERBICIDAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM | RHONE-POULENC AGROCHIMIE (FR) | 1993-03-24 | — | — | EP | disclosed |
| EP-0398818-A1 | Dihalogenated herbicidal sulfones | RHONE-POULENC AGROCHIMIE (FR) | 1990-11-22 | — | — | EP | disclosed |
| EP-0351332-A1 | Herbicidal compounds and compositions containing them | RHONE-POULENC AGROCHIMIE (FR) | 1990-01-17 | — | — | EP | disclosed |