SCHEMBL51464

SCHEMBL51464

CCn1c(C)c(C2(c3c(C)n(CC)c4ccccc34)OC(=O)c3ccccc32)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.46
NPSR1 Q6W5P4 4/20 0.46
ALDH1A1 P00352 4/20 0.44
CFTR P13569 1/20 0.43
GOPC Q9HD26 1/20 0.43
MAPT P10636 5/20 0.41
POLB P06746 3/20 0.41
GPR55 Q9Y2T6 2/20 0.41
ALOX12 P18054 1/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP3A4 P08684 4/20 0.40
TP53 P04637 2/20 0.40
ALOX15 P16050 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362225 1.00 LMNA (0.46) LMNANPSR1ALDH1A1CFTRGOPC
SCHEMBL10937717 0.94 LMNA (0.41) LMNANPSR1ALDH1A1CFTRGOPC
SCHEMBL8608974 0.92 PGR (0.44) LMNANPSR1ALDH1A1POLBTDP1
SCHEMBL3219184 0.90 LMNA (0.44) LMNANPSR1ALDH1A1CFTRGOPC
SCHEMBL11713414 0.89 LMNA (0.38) LMNANPSR1ALDH1A1CFTRGOPC
SCHEMBL29361500 0.88 PGR (0.47) LMNANPSR1ALDH1A1CFTRGOPC
SCHEMBL27560 0.88 PGR (0.47) LMNANPSR1ALDH1A1CFTRGOPC
SCHEMBL10933942 0.87 ALDH1A1 (0.47) LMNANPSR1ALDH1A1CFTRGOPC
SCHEMBL2048334 0.87 CNR2 (0.47) PGR
SCHEMBL25194171 0.86 LMNA (0.43) LMNANPSR1ALDH1A1CFTRGOPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3083262-B1 THERMAL RECORDING MATERIALS APPVION OPERATIONS INC (US) 2019-06-26 EP claimed
EP-3083262-A1 THERMAL RECORDING MATERIALS APPVION, INC. (US) 2016-10-26 EP claimed
US-9126451-B2 Thermal recording materials APPVION, INC. (US) 2015-09-08 US claimed
US-20150165806-A1 THERMAL RECORDING MATERIALS APPVION, INC. (US) 2015-06-18 US claimed
US-20090047599-A1 NEGATIVE-WORKING IMAGEABLE ELEMENTS AND METHODS OF USE EASTMAN KODAK COMPANY 2009-02-19 US claimed
WO-2009023112-A1 NEGATIVE-WORKING IMAGEABLE ELEMENTS AND METHODS OF USE EASTMAN KODAK COMPANY (US) 2009-02-19 WO claimed
US-20030207787-A1 Composition capable of indicating by color change when consumer articles, particularly volatile material dispensers, containing or associated with the composition have become inefficient in use. The composition includes:a volatile and FIRMENICH SA (CH) 2003-11-06 US claimed
US-20020110498-A1 Compositions able to indicate when they become inefficient in use FIRMENICH SA (CH) 2002-08-15 US claimed
US-6284706-B1 COLOR DEVELOPMENT LAYER ON SUBSTRATE NIPPON PAPER INDUSTRIES CO LTD (JP) 2001-09-04 US claimed
EP-0319283-B1 THERMALLY RESPONSIVE RECORD MATERIAL APPLETON PAPERS INC. (US) 1993-06-09 EP claimed
EP-0161105-B1 RECORD MATERIAL APPLETON PAPERS INC. (US) 1989-12-20 EP claimed
EP-0182861-B1 MARKING LIQUID COMPOSITION NCR CORPORATION (US) 1989-07-19 EP claimed
EP-0319283-A2 Thermally responsive record material APPLETON PAPERS INC. (US) 1989-06-07 EP claimed
EP-0165041-B1 RECORD MATERIAL APPLETON PAPERS INC. (US) 1989-01-04 EP claimed
EP-0066955-B1 DIELECTRIC RECORD MATERIAL APPLETON PAPERS INC. (US) 1987-01-28 EP claimed
EP-0165041-A2 Record material APPLETON PAPERS INC. (US) 1985-12-18 EP claimed
EP-0161105-A2 Record material APPLETON PAPERS INC. (US) 1985-11-13 EP claimed
EP-0102132-A1 Reusable, heat-sensitive material APPLETON PAPERS INC. (US) 1984-03-07 EP claimed
US-4423116-A HEAT SENSITIVE CHROMOGENIC COMPOUND AND COLOR DEVELOPER IN BINDER APPLETON PAPERS INC. (US) 1983-12-27 US claimed
US-3940275-A Record material and marking liquid NCR CORPORATION (US) 1976-02-24 US claimed