Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.59 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54329 | 0.90 | RAB9A (0.55) | DDAH1RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL29812612 | 0.90 | RAB9A (0.55) | DDAH1RAB9ANPC1ALDH1A1MAPT | |
| Water SCHEMBL8700534 | 0.88 | ALDH1A1 (0.53) | DDAH1RAB9ANPC1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28286069 | 0.88 | RAB9A (0.53) | DDAH1RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL11740091 | 0.88 | RAB9A (0.53) | DDAH1RAB9ANPC1ALDH1A1MAPT | |
| Methane SCHEMBL29136468 | 0.88 | RAB9A (0.53) | DDAH1RAB9ANPC1ALDH1A1MAPT | |
| 2-Mercaptobenzothiazole SCHEMBL28072415 | 0.79 | DDAH1 (0.57) | DDAH1ACP1RAB9ANPC1ALDH1A1 | |
| Phosphoric Acid SCHEMBL29249074 | 0.79 | DDAH1 (0.57) | DDAH1ACP1RAB9ANPC1ALDH1A1 | |
| SCHEMBL8667039 | 0.77 | DDAH1 (0.74) | DDAH1ACP1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11162902 | 0.75 | RAB9A (0.47) | RAB9ANPC1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518301-B2 | Aptamer for detection of alpha-methylacyl-CoA racemase and diagnostic kit thereof | NATIONAL TAIWAN UNIVERSITY (TW) | 2016-12-13 | — | — | US | disclosed |
| US-20160177397-A1 | APTAMER FOR DETECTION OF ALPHA-METHYLACYL-COA RACEMASE AND DIAGNOSTIC KIT THEREOF | NATIONAL TAIWAN UNIVERSITY (TW) | 2016-06-23 | — | — | US | disclosed |
| EP-1802974-A1 | ANALYTICAL DEVICES WITH PRIMARY AND SECONDARY FLOW PATHS | QUIDEL CORPORATION (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006039542-A1 | ANALYTICAL DEVICES WITH PRIMARY AND SECONDARY FLOW PATHS | QUIDEL CORPORATION (US) | 2006-04-13 | — | — | WO | disclosed |