SCHEMBL5147356

SCHEMBL5147356

O=CCc1sccc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.43
PTGS2 P35354 1/20 0.38
PTPN1 P18031 1/20 0.37
FABP4 P15090 1/20 0.33
FABP5 Q01469 1/20 0.33
PDPK1 O15530 1/20 0.33
KMT2A Q03164 3/20 0.33
RXFP1 Q9HBX9 2/20 0.33
PTGS1 P23219 1/20 0.33
PTPRC P08575 1/20 0.32
TP53 P04637 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9808839 0.81 BCAT2 (0.40) BCAT2PTGS2PTPN1FABP4FABP5
SCHEMBL5146089 0.78 PTGS2 (0.47) PTGS2PTPN1PTGS1ALDH1A1
SCHEMBL5107107 0.76 BCAT2 (0.48) BCAT2PTGS2PTPN1FABP4FABP5
SCHEMBL9439516 0.74 BCAT2 (0.51) BCAT2PTPN1KMT2ARXFP1PTGS1
SCHEMBL27816699 0.72 BCAT2 (0.41) BCAT2PTGS2PTPN1PDPK1RXFP1
SCHEMBL2461016 0.71 BCAT2 (0.47) BCAT2PTGS2FABP4FABP5PDPK1
Acrylic Acid SCHEMBL28813622 0.70 BCAT2 (0.44) BCAT2PTGS2PTPN1FABP4FABP5
SCHEMBL7023782 0.69 CCNB2 (0.46) KMT2AMAPK1ALDH1A1L3MBTL1MEN1
SCHEMBL3358969 0.69 BCAT2 (0.48) BCAT2PTGS2FABP4FABP5PDPK1
SCHEMBL6206041 0.68 DPP4 (0.54) KMT2AMAPK1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114144062-A Pesticidal formulations 石原产业株式会社 2022-03-04 CN disclosed
EP-1831207-A1 AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE Amgen Inc. (US) 2007-09-12 EP disclosed
WO-2006066172-A1 AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE AMGEN, INC. (US) 2006-06-22 WO disclosed