Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 5/20 | 0.76 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.76 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.60 |
| ▸ | MMP1 | P03956 | 5/20 | 0.58 |
| ▸ | MMP2 | P08253 | 5/20 | 0.58 |
| ▸ | MMP9 | P14780 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 1/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2274109 | 1.00 | TRPM2 (0.76) | TRPM2LTB4RTRPA1TRPM8MMP1 | |
| SCHEMBL2271170 | 0.96 | TRPM2 (0.70) | TRPM2LTB4RTRPA1TRPM8MMP1 | |
| SCHEMBL2271172 | 0.96 | TRPM2 (0.70) | TRPM2LTB4RTRPA1TRPM8MMP1 | |
| SCHEMBL2269338 | 0.92 | TRPM2 (0.75) | TRPM2LTB4RTRPA1TRPM8MMP1 | |
| SCHEMBL2269335 | 0.92 | TRPM2 (0.75) | TRPM2LTB4RTRPA1TRPM8MMP1 | |
| SCHEMBL2271620 | 0.89 | TRPA1 (0.73) | TRPM2LTB4RTRPA1TRPM8MMP1 | |
| SCHEMBL2271618 | 0.89 | TRPA1 (0.73) | TRPM2LTB4RTRPA1TRPM8MMP1 | |
| SCHEMBL28809051 | 0.87 | TRPM2 (1.00) | TRPM2LTB4RTRPA1TRPM8MEN1 | |
| SCHEMBL28809046 | 0.87 | TRPM2 (1.00) | TRPM2LTB4RTRPA1TRPM8MEN1 | |
| SCHEMBL9973825 | 0.87 | TRPM2 (0.62) | TRPM2LTB4RTRPA1TRPM8MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094829-B | novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| US-7999132-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| CN-101094829-A | Novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP26, MMP11 | TRPM2 3539/4885LTB4R 2902/4885TRPA1 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.