Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ITGAM | P11215 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147466 | 1.00 | MEN1 (0.44) | MEN1KMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL5145012 | 0.87 | MEN1 (0.42) | MEN1KMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL5145398 | 0.84 | ENPP2 (0.43) | MEN1KMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL5146594 | 0.83 | ALDH1A1 (0.55) | MEN1KMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL14426477 | 0.70 | KMT2A (0.68) | MEN1KMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL6393742 | 0.69 | TDP1 (0.79) | MEN1KMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL6393226 | 0.69 | TDP1 (0.79) | MEN1KMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL5143420 | 0.65 | PIM1 (0.46) | MEN1KMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL14291459 | 0.64 | MEN1 (0.69) | MEN1KMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL14363094 | 0.64 | L3MBTL1 (0.50) | MEN1KMT2APOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718308-A4 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PAINCEPTOR PHARMA CORP (CA) | 2007-07-18 | — | — | EP | disclosed |
| EP-1718308-A2 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PainCeptor Pharma Corp. (CA) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005076695-A2 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PAINCEPTOR PHARMA CORPORATION (CA) | 2005-08-25 | — | — | WO | disclosed |