SCHEMBL5147480

SCHEMBL5147480

Cc1ccc(N)c(CC(O)CO)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
THRB P10828 1/20 0.42
ALDH1A1 P00352 2/20 0.38
HSD17B10 Q99714 1/20 0.38
TAAR1 Q96RJ0 1/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
CA1 P00915 1/20 0.33
AMY1A P0DUB6 1/20 0.33
TSHR P16473 1/20 0.33
ATP4A P20648 1/20 0.33
ATP4B P51164 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
MAPK1 P28482 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28518183 0.83 ALOX15 (0.37) ALOX15TDP1CYP3A4SMN1; SMN2TP53
SCHEMBL33610 0.83 ALOX15 (0.46) ALOX15TDP1CYP3A4SMN1; SMN2TP53
SCHEMBL6369444 0.81 ALOX15 (0.45) ALOX15TDP1CYP3A4SMN1; SMN2TP53
SCHEMBL2877038 0.81 CYP3A4 (0.38) ALOX15TDP1CYP3A4THRBALDH1A1
SCHEMBL10590792 0.77 SLC6A4 (0.38) CYP3A4
SCHEMBL4979889 0.77 MAPK8 (0.36) CYP3A4SMN1; SMN2TAAR1NPC1RAB9A
SCHEMBL356244 0.77 ALOX15 (0.52) ALOX15TDP1CYP3A4SMN1; SMN2TP53
SCHEMBL11794904 0.76 TRPA1 (0.43) ALOX15TDP1CYP3A4TP53ALDH1A1
SCHEMBL17063467 0.76 TSHR (0.36) ALOX15TDP1CYP3A4SMN1; SMN2TP53
Hydrochloric Acid SCHEMBL7394868 0.74 TDP1 (0.45) ALOX15TDP1CYP3A4SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178730-A Anti-fouling marking paint and preparation method and application thereof 湖南驰邦新材料有限公司 2023-05-30 CN claimed
CN-113980569-B Traffic pavement modified marking paint and preparation method thereof 浙江欧路德交通科技有限公司 2022-09-16 CN claimed
CN-113980569-A Traffic pavement modified marking paint and preparation method thereof 浙江欧路德交通科技有限公司 2022-01-28 CN claimed
CN-112920670-A Traffic pavement marking paint 广东美涂士建材股份有限公司 2021-06-08 CN claimed
EP-1469021-B1 (Meth)acrylate resin and its use ALTECO TECHNIK GMBH (DE) 2014-04-23 EP claimed
EP-1786842-A4 METHOD FOR PRODUCING AN (METH)ACRYLATE SYRUP LG CHEMICAL LTD (KR) 2007-10-10 EP claimed
EP-1246651-A4 BIOACTIVE AND OSTEOPOROTIC BONE CEMENT HANTAK ORTHO TECHNOLOGY LTD (CN) 2007-09-26 EP claimed
EP-1786842-A1 METHOD FOR PRODUCING AN (METH)ACRYLATE SYRUP LG Chem Ltd. (KR) 2007-05-23 EP claimed
WO-2006043751-A1 METHOD FOR PRODUCING AN (METH)ACRYLATE SYRUP LG CHEM, LTD. (KR) 2006-04-27 WO claimed
JP-2003518989-A 2003-06-17 JP claimed
EP-1246651-A2 BIOACTIVE AND OSTEOPOROTIC BONE CEMENT Hantak Ortho-Technology Limited (CN) 2002-10-09 EP claimed
US-6270751-B1 VISCOSITY MODIFYING AGENT HAVING ONE OR MORE OF 0.0005 TO 10 VOL % TOLUENESULFONAMIDE EPOXY RESIN AND 0.005 TO 50 VOL % N-ETHYL O/P TOLUENESULFONAMIDE RESLER RENEE (US) 2001-08-07 US claimed
WO-2001049327-A2 BIOACTIVE AND OSTEOPROROTIC BONE CEMENT HKU/HANTAK ORTHO-TECHNOLOGY LIMITED (DE) 2001-07-12 WO claimed
US-5650138-A ACTIVATOR FOR CURING A GEL COMPRISING A SOLVENT, A POLYMERIZATION INITIATOR AND A VISCOSITY MODIFIER RESLER RENEE (US) 1997-07-22 US claimed
CN-116178730-A Anti-fouling marking paint and preparation method and application thereof 湖南驰邦新材料有限公司 2023-05-30 CN disclosed
EP-4177235-A1 PULVERIZED RECYCLED MATERIALS AS FILLERS FOR MULTICOMPONENT SYSTEMS FOR CHEMICAL FIXATION HILTI Aktiengesellschaft (LI) 2023-05-10 EP disclosed
CN-113980569-B Traffic pavement modified marking paint and preparation method thereof 浙江欧路德交通科技有限公司 2022-09-16 CN disclosed
EP-2990061-A1 Radiopaque composition and preparation thereof Maastricht University (NL) 2016-03-02 EP disclosed
US-6270751-B1 VISCOSITY MODIFYING AGENT HAVING ONE OR MORE OF 0.0005 TO 10 VOL % TOLUENESULFONAMIDE EPOXY RESIN AND 0.005 TO 50 VOL % N-ETHYL O/P TOLUENESULFONAMIDE RESLER RENEE (US) 2001-08-07 US disclosed
US-5650138-A ACTIVATOR FOR CURING A GEL COMPRISING A SOLVENT, A POLYMERIZATION INITIATOR AND A VISCOSITY MODIFIER RESLER RENEE (US) 1997-07-22 US disclosed