SCHEMBL356244

SCHEMBL356244

Cc1ccc(N)c(CO)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CYP3A4 P08684 2/20 0.52
TP53 P04637 1/20 0.52
THRB P10828 1/20 0.52
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 1/20 0.46
TAAR1 Q96RJ0 1/20 0.42
CA1 P00915 1/20 0.40
NPC1 O15118 3/20 0.39
RAB9A P51151 2/20 0.39
AMY1A P0DUB6 1/20 0.39
TSHR P16473 1/20 0.39
MAPT P10636 2/20 0.38
MAPK1 P28482 2/20 0.38
PKM P14618 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ATP4A P20648 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28536484 0.90 ALOX15 (0.43) ALOX15TDP1SMN1; SMN2CYP3A4TP53
SCHEMBL1173554 0.83 ALOX15 (0.48) ALOX15TDP1SMN1; SMN2CYP3A4TP53
SCHEMBL2889115 0.82 ALOX15 (0.52) ALOX15TDP1SMN1; SMN2CYP3A4TP53
SCHEMBL12463289 0.81 ALOX15 (0.56) ALOX15TDP1SMN1; SMN2CYP3A4TP53
SCHEMBL19526504 0.79 ALOX15 (0.45) ALOX15TDP1SMN1; SMN2CYP3A4TP53
SCHEMBL1352508 0.79 TDP1 (0.54) ALOX15TDP1SMN1; SMN2CYP3A4TP53
SCHEMBL3682215 0.79 TDP1 (0.54) ALOX15TDP1SMN1; SMN2CYP3A4TP53
SCHEMBL11841401 0.78 TDP1 (0.48) ALOX15TDP1SMN1; SMN2CYP3A4TP53
SCHEMBL30150898 0.78 AMY1A (0.43) ALOX15TDP1TP53ALDH1A1HSD17B10
SCHEMBL233241 0.78 AMY1A (0.43) ALOX15TDP1TP53ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3911795-B1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2025-10-01 EP claimed
CN-113646479-B Method for strengthening non-keratin fibers and use thereof 埃斯普投资有限公司 2023-06-13 CN claimed
US-20220120031-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2022-04-21 US claimed
EP-3911795-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP Investments LLC (US) 2021-11-24 EP claimed
CN-113646479-A Method for strengthening non-keratin fibers and use thereof 埃斯普投资有限公司 2021-11-12 CN claimed
EP-3565523-B1 METHOD FOR COLORING OR BLEACHING HAIR FIBERS HERCULES LLC (US) 2021-09-08 EP claimed
WO-2020150384-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2020-07-23 WO claimed
EP-3565523-A1 METHOD FOR COLORING OR BLEACHING HAIR FIBERS Hercules LLC (US) 2019-11-13 EP claimed
EP-1773768-B1 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2018-08-22 EP claimed
WO-2018129441-A1 METHOD FOR COLORING OR BLEACHING HAIR FIBERS HERCULES LLC (US) 2018-07-12 WO claimed
US-7547713-B2 O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives GU LIANQUAN 2009-06-16 US claimed
EP-1773768-A4 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2008-08-06 EP claimed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP claimed
CN-1284773-C Ortho-pyridinequinone derivative, composite containing said derivative, its preparation method and application BAIRUI GLOBAL CO LTD (VG) 2006-11-15 CN claimed
US-20060111405-A1 O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives GU LIANQUAN 2006-05-25 US claimed
WO-2006012642-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS, INC. (US) 2006-02-02 WO claimed
EP-1422218-A1 ANTIVIRAL AGENT SHIONOGI & CO., LTD. (JP) 2004-05-26 EP claimed
CN-1477099-A O-pyridinoquinone derivative, composition containing the same, preparation method and use of the same 百瑞全球有限公司 2004-02-25 CN claimed
US-6509393-B2 Phase change inks XEROX CORPORATION 2003-01-21 US claimed
US-20020137816-A1 Phase change inks XEROX CORPORATION 2002-09-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111405-A1 O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives PTGS2, PTGES2, PTGES ALOX15 227/4885TDP1 3288/4885SMN1; SMN2 3704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.