Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | EDNRA | P25101 | 5/20 | 0.43 |
| ▸ | EDNRB | P24530 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240985 | 0.86 | CASP1 (0.56) | CASP1BCAT2MEN1KMT2AEDNRA | |
| SCHEMBL9682375 | 0.85 | CASP1 (0.49) | CASP1BCAT2EDNRAEDNRBBCL2 | |
| SCHEMBL5147607 | 0.83 | CASP1 (0.54) | CASP1EDNRAEDNRBCA1CA2 | |
| SCHEMBL10729804 | 0.80 | CA1 (0.55) | MEN1KMT2ACA1CA2MMP1 | |
| SCHEMBL10916572 | 0.80 | CASP1 (0.51) | CASP1EDNRAEDNRBFGFR1SRC | |
| SCHEMBL10915661 | 0.80 | CASP1 (0.45) | CASP1BCAT2MEN1KMT2AEDNRA | |
| SCHEMBL29537027 | 0.80 | CA2 (0.58) | CASP1EDNRAEDNRBCA1CA2 | |
| SCHEMBL1767981 | 0.80 | CA2 (0.58) | CASP1EDNRAEDNRBCA1CA2 | |
| SCHEMBL8997291 | 0.79 | CASP1 (0.50) | CASP1EDNRAEDNRBCA1CA2 | |
| SCHEMBL418847 | 0.78 | CASP1 (0.51) | CASP1EDNRAEDNRBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4586951-A | PLANT GROWTH REGULATORS FOR RICE FIELDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-05-06 | — | — | US | claimed |
| EP-0560177-B1 | Imidazole derivatives having biphenylsulphonylurea or biphenylsulfonylurethane side chains, process for their production and use thereof | HOECHST AG (DE) | 2003-01-08 | — | — | EP | disclosed |
| EP-1183236-A1 | CINNAMOYLAMINOALKYL-SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES | Aventis Pharma Deutschland GmbH (DE) | 2002-03-06 | — | — | EP | disclosed |
| US-6350778-B1 | CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-02-26 | — | — | US | disclosed |
| WO-2000071513-A1 | CINNAMOYLAMINOALKYL-SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-30 | — | — | WO | disclosed |
| US-5604251-A | Imidazole derivatives with a biphenylsulfonylurea or biphenylsulfonylurethane side chain and their use as angitensin II receptors | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-18 | — | — | US | disclosed |
| US-5604251-A | Imidazole derivatives with a biphenylsulfonylurea or biphenylsulfonylurethane side chain and their use as angitensin II receptors | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-18 | — | — | US | disclosed |
| US-5604251-A | Imidazole derivatives with a biphenylsulfonylurea or biphenylsulfonylurethane side chain and their use as angitensin II receptors | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-18 | — | — | US | disclosed |
| EP-0560177-A1 | Imidazole derivatives having biphenylsulphonylurea or biphenylsulfonylurethane side chains, process for their production and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |
| US-4810282-A | 3-ORTHO-(ISOXAZOLYL,ISOTHIAZOLYL, PYRAZOLYL,THIADIAZOLYL, OXADIAZOLYL AND TRIAZOLYL BENZENESULFONUREYLENE-1,2,4-TRIAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| US-4695311-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-22 | — | — | US | disclosed |
| US-4606755-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
| US-4600792-A | PHENYL 2-BIPHENYLYLSULFONYLCARBAMATE, HERBICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-07-15 | — | — | US | disclosed |
| US-4600792-A | PHENYL 2-BIPHENYLYLSULFONYLCARBAMATE, HERBICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-07-15 | — | — | US | disclosed |
| US-4592775-A | Containing hetero ring substitution | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0158248-A3 | PROCESS FOR THE PREPARATION OF BIPHENYLSULFONYL UREA DERIVATIVES, THEIR INTERMEDIATES AND PROCESS FOR THE PREPARATION OF THE INTERMEDIATES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-02-12 | — | — | EP | disclosed |
| EP-0158248-A2 | Process for the preparation of biphenylsulfonyl urea derivatives, their intermediates and process for the preparation of the intermediates | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-10-16 | — | — | EP | disclosed |
| US-4511392-A | N--/PYRIMIDIN-2-YLAMINOCARBENYL/-HETERO-SUBSTITUETED BENZENSESULFO | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-16 | — | — | US | disclosed |
| US-4460401-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0083975-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |