SCHEMBL5148121

SCHEMBL5148121

COC(=O)C(C)(C)P(=O)(O)OBr

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10947345 0.82 DGAT1 (0.38) DGAT1
SCHEMBL8346130 0.78 DGAT1 (0.35) DGAT1
SCHEMBL992 0.77 DGAT1 (0.41) DGAT1
SCHEMBL9697626 0.75 DGAT1 (0.39) DGAT1
SCHEMBL9066294 0.70 DGAT1 (0.39) DGAT1
Phosphoric Acid SCHEMBL28716950 0.69 DGAT1 (0.42) DGAT1
Phosphoric Acid SCHEMBL29828181 0.69 DGAT1 (0.42) DGAT1
SCHEMBL3178598 0.65 L3MBTL1 (0.35) DGAT1
SCHEMBL5164127 0.65 DGAT1 (0.39) DGAT1
SCHEMBL7019538 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1483253-A4 AN ANTIMICROBIAL AGENT UNIV GRIFFITH (AU) 2007-03-21 EP disclosed
CN-1871247-A Novel sulfenamides UNIV GRIFFITH (AU) 2006-11-29 CN disclosed
EP-1664072-A1 NOVEL SULFENAMIDES GRIFFITH UNIVERSITY (AU) 2006-06-07 EP disclosed
WO-2006037185-A1 NOVEL SULFENAMIDES AND SULFENAMIDE OXIDES GRIFFITH UNIVERSITY (AU) 2006-04-13 WO disclosed
US-20050124559-A1 Antimicrobial agent UNIVERSITY, MONASH (AU) 2005-06-09 US disclosed
WO-2005019237-A1 NOVEL SULFENAMIDES GRIFFITH UNIVERSITY (AU) 2005-03-03 WO disclosed
EP-1483253-A1 AN ANTIMICROBIAL AGENT GRIFFITH UNIVERSITY (AU) 2004-12-08 EP disclosed
WO-2003070715-A1 AN ANTIMICROBIAL AGENT GRIFFITH UNIVERSITY (AU) 2003-08-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124559-A1 Antimicrobial agent OXSR1, OSBPL3, SIGMAR1 DGAT1 2203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.