SCHEMBL9066294

SCHEMBL9066294

COC(=O)C(C)(C)P(=O)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.35
KCNN4 O15554 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10947345 0.78 DGAT1 (0.38) DGAT1L3MBTL1KCNN4
SCHEMBL992 0.77 DGAT1 (0.41) DGAT1L3MBTL1KCNN4ALDH1A1
SCHEMBL5665801 0.77 L3MBTL1 (0.32) L3MBTL1ALDH1A1
SCHEMBL3178600 0.77 ALDH1A1 (0.36) L3MBTL1ALDH1A1
SCHEMBL9697626 0.75 DGAT1 (0.39) DGAT1L3MBTL1KCNN4ALDH1A1
SCHEMBL9770200 0.73 KCNN4 (0.34) DGAT1L3MBTL1KCNN4
SCHEMBL6120239 0.73 L3MBTL1 (0.34) DGAT1L3MBTL1KCNN4
SCHEMBL10403439 0.70 TSHR (0.34) DGAT1
SCHEMBL21562601 0.70 DGAT1 (0.32) DGAT1
SCHEMBL7371583 0.70 DGAT1 (0.32) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0690890-A1 PHOSPHORUS-CONTAINING FLAME RETARDANTS COURTAULDS PLC (GB) 1996-01-10 EP disclosed
WO-1994021724-A1 PHOSPHORUS-CONTAINING FLAME RETARDANTS COURTAULDS PLC (GB) 1994-09-29 WO disclosed