Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 6/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 6/20 | 0.48 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.48 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5148241 | 0.89 | KCNJ6 (0.54) | KCNJ6KCNJ3KCNJ5GSTO1CA12 | |
| SCHEMBL5151701 | 0.86 | TBXA2R (0.48) | CA12CA1CA2CA9TBXA2R | |
| SCHEMBL5149550 | 0.81 | PNLIP (0.39) | CA12CA1CA2CA9TBXA2R | |
| SCHEMBL4232176 | 0.80 | FPR2 (0.46) | ALDH1A1LMNASMN1; SMN2MEN1MAPK1 | |
| SCHEMBL5181890 | 0.80 | PNLIP (0.55) | — | |
| SCHEMBL5149668 | 0.79 | BRAF (0.49) | CA12CA1CA2CA9MMP2 | |
| SCHEMBL4684325 | 0.79 | MAPK1 (0.43) | CA12CA1CA2CA9TBXA2R | |
| SCHEMBL5180344 | 0.78 | MMP2 (0.42) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL13699200 | 0.78 | MAPK1 (0.42) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL4234256 | 0.77 | MAPK1 (0.56) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |