Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.57 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20930858 | 0.91 | ERCC1 (0.58) | ERCC1ERCC4FFAR4LMNANOTUM | |
| SCHEMBL15021326 | 0.86 | ERCC1 (0.52) | ERCC1ERCC4FFAR4LMNANOTUM | |
| Benzene SCHEMBL28260772 | 0.86 | ERCC1 (0.51) | ERCC1ERCC4FFAR4LMNANOTUM | |
| SCHEMBL27373948 | 0.84 | ERCC1 (0.53) | ERCC1ERCC4FFAR4LMNANOTUM | |
| SCHEMBL5934873 | 0.84 | NOTUM (0.57) | ERCC1ERCC4FFAR4LMNANOTUM | |
| SCHEMBL15021544 | 0.84 | ERCC1 (0.52) | ERCC1ERCC4FFAR4LMNANOTUM | |
| SCHEMBL13734402 | 0.83 | ERCC1 (0.52) | ERCC1ERCC4FFAR4LMNANOTUM | |
| SCHEMBL514359 | 0.82 | NOTUM (0.62) | FFAR4NOTUMMAPK1HTTMAPT | |
| SCHEMBL21031161 | 0.82 | FFAR4 (0.44) | ERCC1ERCC4FFAR4LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL6006151 | 0.82 | NOTUM (0.55) | ERCC1ERCC4FFAR4LMNANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | UNIV SOUTHERN CALIFORNIA (US) | 2020-12-10 | — | — | US | disclosed |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | UNIV SOUTHERN CALIFORNIA (US) | 2020-12-10 | — | — | US | disclosed |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2020-08-11 | — | — | US | disclosed |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2020-08-11 | — | — | US | disclosed |
| EP-3109238-B1 | PHENYL-PYRAZOLE COMPLEXES OF IRIDIUM | UNIV SOUTHERN CALIFORNIA (US) | 2019-09-18 | — | — | EP | disclosed |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2018-01-18 | — | — | US | disclosed |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2018-01-18 | — | — | US | disclosed |
| US-9583720-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-02-28 | — | — | US | disclosed |
| US-9583720-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-02-28 | — | — | US | disclosed |
| EP-3109238-A1 | PHENYL-PYRAZOLE COMPLEXES OF IRIDIUM | University of Southern California (US) | 2016-12-28 | — | — | EP | disclosed |
| EP-2062908-A1 | Complexes of iridium comprising pyrazolylcarbazole ligands | University of Southern California (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20080176102-A1 | Organic light emitting devices; electroluminescent efficiency, durability; such as tris(1-(4-biphenyl)pyrazolato)iridium complexes | THOMPSON MARK E | 2008-07-24 | — | — | US | disclosed |
| US-7338722-B2 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-03-04 | — | — | US | disclosed |
| US-7332233-B2 | Iridium compound and organic electroluminescent device using the same | SAMSUNG SDI CO., LTD. (KR) | 2008-02-19 | — | — | US | disclosed |
| US-7332233-B2 | Iridium compound and organic electroluminescent device using the same | SAMSUNG SDI CO., LTD. (KR) | 2008-02-19 | — | — | US | disclosed |
| US-7332233-B2 | Iridium compound and organic electroluminescent device using the same | SAMSUNG SDI CO., LTD. (KR) | 2008-02-19 | — | — | US | disclosed |
| EP-1606296-A2 | PHENYL-PYRAZOLE COMPLEXES OF Ir | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-12-21 | — | — | EP | disclosed |
| US-20050031903-A1 | Iridium compound and organic electroluminescent device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2005-02-10 | — | — | US | disclosed |
| US-20040253478-A1 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | UNIVERSITY OF SOUTHERN CALIFORNIA, THE | 2004-12-16 | — | — | US | disclosed |
| WO-2004085450-A2 | PHENYL-PYRAZOLE COMPLEXES OF IR | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040253478-A1 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | NR2E3, IK, NR2C2 | ERCC1 1124/4885ERCC4 2126/4885FFAR4 2502/4885 |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | EML4, RCOR3, CPNE4 | ERCC1 461/4885ERCC4 173/4885FFAR4 1632/4885 |
| US-20050031903-A1 | Iridium compound and organic electroluminescent device using the same | IK, ALPL, PPIP5K2 | ERCC1 241/4885ERCC4 628/4885FFAR4 4347/4885 |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | EML4, AFF4, RCOR3 | ERCC1 344/4885ERCC4 607/4885FFAR4 1057/4885 |
| US-20080176102-A1 | Organic light emitting devices; electroluminescent efficiency, durability; such as tris(1-(4-biphenyl)pyrazolato)iridium complexes | EML4, RNF4, LIG4 | ERCC1 111/4885ERCC4 290/4885FFAR4 1231/4885 |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | EML4, AFF4, RCOR3 | ERCC1 344/4885ERCC4 607/4885FFAR4 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.